Cancer is a tricky foe, but scientists are making progress. A new vaccine called ELI-002 is showing promise in fighting back against pancreatic and colorectal cancers. This vaccine is special because it's designed to work for many people right away, not just one person at a time. The vaccine targets a common mutation called KRAS, which is often found in these types ...
Biliary tract cancer (BTC) has long been a challenging disease to treat. Traditionally, doctors relied on a combination of cisplatin and gemcitabine as the go-to treatment. But things are changing. Adding durvalumab, a type of immunotherapy, to this mix has shown promising results. It's making a real difference in how long patients live. So, what's the big deal abou...
In the fight against cancer, scientists are always looking for new ways to make treatments work better. One big challenge is that cancer cells can become resistant to drugs over time. To tackle this, researchers have come up with a clever idea: combining two powerful tools to attack cancer cells from different angles. First, they created a special drug called a circ...
Lung cancer is a serious disease. Doctors often use a mix of treatments to fight it. One common approach is neoadjuvant chemoimmunotherapy. This treatment happens before surgery. It aims to shrink tumors and make them easier to remove. But how long should this treatment last? That's a big question. Right now, there's no clear answer. Different doctors might suggest ...
Scientists have come up with a clever way to fight cancer using a special molecule. This molecule can find and attack cancer cells in the body. The tricky part about cancer is that it can hide from the body’s defense system. But this new treatment helps the body recognize and fight cancer cells. The researchers at Stanford made this new treatment by combining two pa...
Cancer treatments are always looking for new tricks. One promising method is photothermal therapy (PTT). It uses light to heat up and kill cancer cells. But there are some problems. Light doesn't go deep into the body. Also, cancer cells can get used to the heat. Scientists have found a clever solution. They made a new tool using ferrocene, a special iron compound. T...
Cholangiocarcinoma (CCA) is a tough cancer to treat. Doctors have a hard time figuring out which treatments will work best for each patient. One big challenge is predicting how well a patient will respond to immunotherapy, a treatment that helps the body's own immune system fight cancer. Researchers are looking into using machine learning to tackle this problem. Mac...
Cancer treatment has seen a big change with immune checkpoint blockade (ICB) therapy. This therapy works by waking up the body's immune system to fight cancer. However, it doesn't always work well with solid tumors. The immune response might not be strong enough. To tackle this, scientists have come up with a clever plan. They combined ICB with a special kind of nano...
In the world of cancer treatments, there is a lot of talk about how to make new drugs work better. One big idea is called performance-based risk-sharing agreements. This is a fancy way of saying that the people who make the drugs and the people who pay for them agree to share the risks and rewards. It is all about making sure that new treatments, like immunotherapy f...
The world of cancer treatment is a complex battlefield. One key player in this fight is the tumor microenvironment (TME). This is the area around a tumor, where various cells and substances interact. These interactions can greatly influence how cancer develops and responds to treatment. The TME is a dynamic place, constantly changing and adapting. It includes blood v...