Losing a partner early in life can be incredibly tough. It brings a lot of stress and can even lead to serious health problems. This isn't just about feeling sad. The body goes through some big changes too. One key change is an increase in inflammation. This isn't the kind of inflammation you see on your skin. It's happening inside your body. It's linked to both hear...
Air pollution has become a major concern for many people. It is a significant issue that affects everyone. It is especially bad for those who suffer from allergies. The tiny particles in the air, known as PM2. 5, are particularly troublesome. They are small enough to get into the body and cause problems. These particles are linked to a higher chance of respirato...
Mice with a specific genetic tweak might hold the key to understanding how to protect the liver from damage. It all starts with a gene called PLA2G6. This gene is linked to a protein that plays a role in inflammation in humans. In mice, when this gene is turned off specifically in certain immune cells, interesting things happen. These immune cells, known as myel...
Atherosclerosis is a condition where fatty deposits build up in the arteries. This can lead to heart disease and stroke. It is well known that disturbed blood flow plays a big role in this process. But what if there is more to the story? What if certain genes also play a part? In recent research, scientists looked into a specific gene called Aff3ir-ORF2. This gene i...
The human body is a marvel of adaptation. It can adjust to various stresses, including physical exertion. One of the ways it does this is through the immune system. Endurance training, in particular, can lead to changes in the immune system. These changes help the body handle the stress of exercise and promote an anti-inflammatory effect. However, the exact proc...
Sepsis is a serious condition that can mess with your brain. It can cause a bunch of problems, like delirium, coma, and even long-term memory issues. Doctors call this sepsis-associated encephalopathy, or SAE. It's a big deal because it affects a lot of people and can be really hard to deal with. SAE is all about the brain's immune cells, called microglia, g...
Trichinella spiralis parasites are sneaky. They trick muscle cells into becoming "nurse cells, " feeding and protecting them. Medicines like verapamil, used for other health issues, might mess with this clever plan. Scientists tested verapamil, ivermectin (IVM), and both together against these parasites in mice. Verapamil didn't bother adult worms in the gut, but it ...