Two treatments, sotorasib and adagrasib, have received approval in the USA and Europe for tackling advanced or metastatic non-small cell lung cancer. This type of cancer is marked by a specific mutation known as KRAS G12C. Since these treatments have not been directly compared in clinical trials, researchers turned to an alternative method. They used a technique call...
LCNEC stands for Large Cell Neuroendocrine Carcinoma. It is a particularly aggressive type of lung cancer. It is a type of non-small cell carcinoma. This type of cancer has been recognized as a distinct tumor for many years. It is a type of cancer that is hard to diagnose and treat. This is because it is made up of a mix of different genetic and epigenetic chang...
A man from New Jersey passed away from a severe lung cancer that doctors suspect might be linked to his long-term use of e-cigarettes. This case is believed to be the first of its kind, raising serious questions about the safety of vaping. The man, who was 51 years old, had been vaping for over a decade after quitting traditional cigarettes in 2009. He first sought ...
Lung cancer is a major health issue. It is the leading cause of cancer deaths worldwide. One type, non-small cell lung cancer (NSCLC), makes up about 85% of all lung cancer cases. This is a big deal because it means most people with lung cancer have this type. The good news is that there are now more targeted treatments available for NSCLC. These treatments can ...
The battle against advanced non-small cell lung cancer (aNSCLC) has seen significant strides with targeted therapies and immunotherapies. These treatments have shown promise in extending the lives of patients. However, there is a catch. The cost of these medications is sky-high. This raises important questions about access and affordability. Patients with aN...
In the world of cancer treatments, there is a lot of talk about how to make new drugs work better. One big idea is called performance-based risk-sharing agreements. This is a fancy way of saying that the people who make the drugs and the people who pay for them agree to share the risks and rewards. It is all about making sure that new treatments, like immunotherapy f...
The U. S. Preventive Services Task Force has a clear recommendation. They suggest that adults aged 50 to 80, who have smoked heavily in the past or currently smoke, should get an annual lung cancer screening. This screening is done using a low-dose computed tomography (LDCT) scan. It is a simple and effective way to catch lung cancer early. However, there is a group...
Sleep apnea, a condition where breathing stops for short periods during sleep, has been linked to cancer. However, the connection is not clear-cut. Some studies suggest a link, while others do not. This is because most studies have been small or not based on the general population. So, a large population-based study was conducted to explore the relationship between s...
Lung cancer is a serious issue worldwide, and a small fraction of cases are driven by something called RET rearrangements. These are like genetic mix-ups that can fuel cancer growth. To fight this, doctors use special drugs known as RET inhibitors. These drugs have been a game-changer for patients, but there's a catch. Over time, the cancer can become resistant to th...
Lung cancer is a complex disease. It is not one-size-fits-all. Stage III non-small cell lung cancer (NSCLC) is a prime example. It is a mixed bag of different subgroups. Some respond well to treatment. Others do not. This is why identifying these subgroups is so important. It helps doctors tailor treatments to each patient's needs. One treatment that has show...