Biopharmaceuticals are on the rise, but they have a big problem—they tend to clump together quickly. Right now, we use surfactants like polysorbates and poloxamers to stop this from happening and make them last longer. However, these surfactants aren't very stable themselves. They change into many d
Imagine you're a doctor. You need to know if a patient's cough or sneeze is just a passing thing or a sign of something bigger. That's where machine learning comes in. Researchers created an automatic system to spot sneezes and coughs, sounds that can hint at respiratory problems. The goal? Early di
Ever wondered why pharmaceutical CEOs might need extra education? Well, it's not just about business and finance anymore. These top bosses often struggle with understanding the complex world of research and development (R&D). Unlike their staff, who spend years learning the ropes, CEOs may not grasp
Scientists often use stem cells to make artificial bones, but making sure these cells develop properly can be tricky. They've tried using omics technologies, like metabolomics, to check their quality. In a recent study, researchers combined metabolomics with machine learning to see if it could tell
IgG4-related disease (IgG4-RD) is a curious immune condition. It makes certain organs swell and not work properly. One big clue is that affected organs grow special lymphoid tissues, called TLTs. Inside these, special helper T cells (Tfh2) turn regular B cells into IgG4+ cells, which cause the swell
Medicines used to treat and prevent heart thrombosis have truly changed the game. They've made a big difference in how patients with heart artery disease do, but they've also made it trickier for doctors to decide on the best treatment. With improved ways to fix heart arteries and better stents, the
You probably know that medications can sometimes have side effects. But do you know about nitrosamines? These are harmful chemicals that can form in drugs. They're not something we want in our medicine. Let's dive into why they're a problem and how we're trying to deal with them. In 2019, some medi
Researchers have come up with a smart new way to figure out how much coastal cliffs are eroding. They combined data from drones, satellites, and laser measurements to see how bad the erosion is. This method helps us understand both natural wear and tear on cliffs and damage to protective structures
Follicular lymphoma (FL) can be a tricky disease. Sometimes, it worsens quickly, within just two years. This is called progression of disease within 24 months (POD24), and it can really affect how long patients live. A group of researchers from China decided to tackle this problem. They wanted to fi
Immuno-oncology drugs, like immune checkpoint inhibitors (ICIs), have shown potential in treating various cancers. For advanced non-small cell lung cancer (NSCLC) patients with PD-L1 expression of 50% or higher, single-drug ICI therapy that targets PD-L1 is the standard treatment. But can machine le
