Laryngeal dystonia (LD) is a tricky condition. It causes sudden muscle spasms in the voice box during speech. This makes talking really hard. People with LD often find it tough to communicate clearly. Recently, sodium oxybate has shown promise as a treatment. It's especially helpful for those who respond to alcohol. But how well does it work over time? A recent study...
Chronic pain affects millions, yet treatments haven't kept up with scientific advances. Experts agree that we know more than ever about pain, but the healthcare system isn't set up to deliver the right care. Nearly one in four adults struggles with chronic pain, a number that's been rising since 2019. As people live longer, conditions like arthritis and degenerative ...
Hereditary angioedema (HAE) is a rare condition that causes painful swelling. Two treatments, garadacimab and lanadelumab, were put to the test to see which one works better. Since there are no direct comparisons, researchers used a clever method called matching-adjusted indirect comparison (MAIC) to make an educated guess. Garadacimab was given once a month, while ...
After surgery, some people experience confusion. This is not a small issue. It can lead to longer hospital stays. It might also cause lasting problems with the brain. The big question is: why do doctors struggle to treat it? Doctors try different medicines. But these treatments are not always effective. They are not backed by strong research. This makes the situatio...
Ankle fractures, specifically Weber B types, can be tricky to fix. Surgeons often debate whether using a special screw, called a lag screw, helps patients heal better. This screw is designed to pull broken bone pieces together, but is it really necessary? Some doctors use it, while others don't. The truth is, there isn't much solid evidence showing that the lag scre...
A study looked at two ways to fix a kidney problem in babies. The problem is called ureteropelvic junction obstruction, or UPJO. This happens when the tube that carries urine from the kidney to the bladder gets blocked. The study compared two types of surgery. One is called laparoscopic pyeloplasty, or LP. The other is robot-assisted single-port laparoscopic pyelopl...
In a small hospital, doctors found something unusual in a 2-month-old girl. She had a large choledochal cyst. This is a rare problem where a cyst grows in the common bile duct. It's more common in girls, especially those from Asian backgrounds. These cysts happen because the pancreas and bile ducts join in the wrong way. If not treated, they can cause big problems, l...
Two treatments, sotorasib and adagrasib, have received approval in the USA and Europe for tackling advanced or metastatic non-small cell lung cancer. This type of cancer is marked by a specific mutation known as KRAS G12C. Since these treatments have not been directly compared in clinical trials, researchers turned to an alternative method. They used a technique call...
In Kathmandu, a significant number of adults are dealing with high blood pressure. This is a serious issue, as it can lead to various health problems if not managed properly. However, many people struggle to stick to their long-term medication plans. This is not just about forgetting to take pills. It's also about beliefs and fears that come from their cultural backg...
The world of medicine is always changing. One hot topic is the use of steroids to treat bad lung infections. These infections are called community-acquired pneumonia, or CAP for short. It is a common illness. It is often caused by bacteria. It can be dangerous. It can make people very sick. So, doctors are always looking for the best ways to treat it. Steroid...