METABOLIC ENGINEERING

May 15 2025SCIENCE

Boosting Vitamin B2 with Smart Bacterial Tweaks

The quest to boost vitamin B2, or riboflavin, production has led to some clever tricks with bacteria. Scientists have found a way to make Bacillus subtilis, a common bacteria, produce more riboflavin. They did this by tweaking a specific pathway in the bacteria's metabolism. This pathway, known as the purine salvage pathway, helps the bacteria save energy while makin...

reading time about 1 minute
May 14 2025SCIENCE

The Secret to Making Andrographolide Without Plants

Andrographolide is a big name in the world of natural medicine. This powerful compound is known for its strong anti-inflammatory effects. It comes from a plant called Andrographis paniculata. For a long time, the only way to get andrographolide was to extract it from this plant. This method has its limits. It relies on growing and harvesting plants, which can be slow...

reading time about 1 minute
Nov 28 2024SCIENCE

Shining a Light on Gene Control in Bacteria

Corynebacterium glutamicum is a critical player in the production of amino acids and valuable chemicals. Balancing the metabolic processes between cell growth and product synthesis is essential for boosting efficiency. The challenge lies in developing effective and safe gene regulation tools that can dynamically control these processes. This study introduces a novel ...

reading time about 1 minute