Designing proteins that are both stable and effective can be a real challenge for scientists. But what if AI could step in and simplify this task? Introducing PRIME, an AI model that harnesses temperature to predict optimal protein modifications. During testing with a variety of proteins, PRIME out
Engrailed homeodomain, or EngHD, is a crucial protein that controls over 200 genes by acting as a transcription factor. It folds quickly, but scientists aren't quite sure how electrostatic interactions within it affect its stability and cooperativity during folding. Recent research used a computer m
Two high school girls, Taylor and Kaitlyn, are standing up for what they believe is fair. They're cross-country runners at Martin Luther King High School in California. They sued their school district because they think a transgender teammate is getting special treatment. The district says this is a
Hey, crime drama fans! If you were hoping to see a new episode of ‘High Potential’ on ABC this Tuesday, November 26, we’ve got some news for you. The good news is that the show is coming back in January 2025. The not-so-good news? You’ll have to wait until then to see what happens next. ‘High Poten
Have you ever heard of a tiny molecule that can trick cells into getting rid of bad proteins? Meet PROTACs, a fascinating concept in biotherapeutics. PROTAC stands for Proteolysis Targeting Chimeras. These clever molecules are designed to lure specific proteins and escort them to the cell's waste di
Imagine this: artists are given special access to a new AI tool called Sora by OpenAI. This tool can turn text into videos, which is super exciting. But here’s the twist. The artists feel like they’re just being used for free labor. They believe OpenAI wants to promote its product using their work,
Imagine trying to stop a virus by blocking a specific part of it. Scientists are investigating drugs that target a protein called 3CL Pro . This protein is vital for the coronavirus to function and is similar across different types of coronaviruses. It's like finding a weak spot on a castle wall a
Ever wondered how microalgae could help protect our skin from the sun? Scientists have been looking into this, focusing on two types: Nannochloropsis oceanica and Chlorococcum amblystomatis. Their lipid extracts can potentially shield our skin from ultraviolet A (UVA) damage. These lipids work by k
Ever wondered how your body might react to a medicine before you take it? That's where personalized medicine comes in. By combining pharmacogenomics (studying how your genes affect your response to drugs) with nanotechnology, scientists are creating something called nano-enabled pharmacogenomics. Th
In a tense situation in Pakistan, four security officers were killed when Imran Khan’s supporters broke through barricades in the capital, Islamabad. The protesters, who want Khan’s release from jail and a change in the government due to alleged election fraud, clashed with law enforcement. The inte
