Heavy metals like lead, cadmium, and mercury are sneaky troublemakers. They hide in food, water, and air, causing serious problems for pregnant women and their babies. These metals can lead to miscarriages, low birth weight, early deliveries, and even developmental issues in kids. They work by creating oxidative stress, which damages DNA and causes all sorts of probl...
In Italy's Veneto Region, PFAS pollution has become a significant issue, affecting both the environment and wildlife. These tough-to-break-down chemicals build up in animals over time, making them a major concern. Freshwater fish, like the European chub, are particularly vulnerable. Researchers wanted to see how these fish cope with long-term PFAS exposure. They loo...
People often wonder how exercise helps the body. It turns out tiny molecules called microRNAs (miRNAs) play a big role. These miRNAs help control a special type of cell death called ferroptosis. This cell death happens when too much iron builds up and causes damage. miRNAs can target important proteins like SLC7A11, GPX4, and ACSL4. These proteins help protect cells ...
Diabetes can cause serious brain issues, making life much harder. The blood-brain barrier, or BBB, is a vital shield that protects the brain. When diabetes is around, this barrier can get damaged, leading to big problems. High blood sugar is the main culprit behind BBB damage. It triggers a chain reaction of harmful events. Oxidative stress, inflammation, and the bu...
The body has a clever way of keeping cells healthy. It uses a tiny helper called cytosolic thioredoxin. This helper is a protein that works hard to keep other proteins in good shape. It does this by converting protein disulfides to thiols. It needs the help of thioredoxin reductase-1 and NADPH to do its job. There is another version of this helper called thioredoxin-...
Chemotherapy is a tough journey. It can mess with your brain, causing memory lapses, trouble focusing, and even feelings of depression and anxiety. This is often called "chemo brain. " Now, there's a drug called rosuvastatin, usually used to lower cholesterol, that might help with this issue. It works by inhibiting an enzyme called HMG-CoA reductase. Scientists wante...
The brain's hippocampus is crucial for learning and memory. It is also very sensitive to stress. One type of stress is being in cold water for a long time. This can harm the hippocampus and affect how well it works. This is because the body's stress response system kicks in, releasing certain hormones that can damage brain cells. Vitamin D is known for its role in b...
The concept of Life's Crucial 9 (LC9) is not new. It is a set of nine lifestyle factors that are believed to influence how quickly a person ages. These factors include diet, physical activity, sleep, and mental health. The idea is that by focusing on these areas, people can slow down the aging process and improve their overall health. The Life's Essential 8 (LE8)...
In the world of medicine, liver damage from drugs is a big deal. It happens when medicines or their byproducts cause harm. This type of damage is linked to something called oxidative stress. To fight this, the body uses sulfhydryl groups. These are like tiny warriors that protect cells from damage. So, keeping an eye on these groups is crucial for understanding and t...
There is a strong link between gum disease and the body's ability to fight off harmful substances. The body's defense system can be weakened by an excess of harmful oxygen compounds and a lack of protective antioxidants. This can lead to serious gum problems. Pranayama is a type of breathing exercise rooted in yoga. It involves controlled, rhythmic, and deep breathin...