PATHOGENESIS

Dec 30 2024HEALTH

Understanding Meniscus Root Tears in India: Patterns and Causes

In India, the meniscus root tears — specifically the medial and lateral ones — are an issue that deserves special attention. These tears can happen due to various reasons and lead to different patterns of damage. Scientists wanted to learn more about why these tears occur and how they look in the Indian population. The meniscus is like a cushion in your knee, and wh...

reading time about 1 minute
Dec 18 2024SCIENCE

How Bacteria Like Salmonella Use Sirtuins to Stay Ahead

Ever wondered how bacteria stay alive inside your body? Salmonella, for one, has a clever trick up its sleeve. It uses two special enzymes, SIRT1 and SIRT3, to mess with your body's energy system. You might know these enzymes as sirtuins. They're like the body's metabolic regulators, helping to control how cells use energy. Scientists found that when Salmonella jump...

reading time about 1 minute
Dec 13 2024SCIENCE

Unraveling CapG: A Staph Enzyme's Unfolding Story

CapG, a key enzyme from Staphylococcus aureus, folds and unfolds in a complex dance. This protein, which helps the bacteria build its defence shield, changes shape based on its concentration and surroundings. Scientists studied a replica of CapG, called rCapG, and found it can exist in many forms, from solo (monomers) to grouped (oligomers like dimers, trimers, tetra...

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Dec 07 2024HEALTH

The Hidden Role of Viruses in Cervical Cancer

Cervical cancer, the most common gynecological cancer worldwide, is on the rise. Researchers are finding that certain viruses, like human papillomavirus (HPV), Epstein-Barr virus (EBV), and others, might be playing a part in this cancer's development. It's crucial to understand how these viruses interact with the body to cause cervical cancer. One way viruses contri...

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Nov 21 2024HEALTH

What's the Link Between Two Enzymes and Lupus?

Ever heard of ACK1 and BRK? These are two non-receptor tyrosine kinases that have been found to play a role in an autoimmune disease called systemic lupus erythematosus (SLE). Scientists have discovered that people with SLE in their families might have issues with these enzymes. When researchers blocked these enzymes in mice, they saw an increase in autoantibodies an...

reading time less than a minute