Brain diseases like Alzheimer's and CTE have something in common: clumps of a protein called tau. These clumps are a big deal in these diseases. Scientists have been trying to figure out how to stop these clumps from forming. One thing they've noticed is that when a specific spot on the tau protein,
The early Earth was a wild place. The planet was full of chemicals that don't exist today. One big mystery is how life started from these chemicals. Scientists have been puzzling over this for a long time. One key question is how phosphorus, an important element for life, got involved in the ear
Temperature plays a significant role in how our genes function. This is especially true for a specific spot in the PDGFRβ gene, where four different changes have been found. These changes, known as p. Asn666Lys, p. Asn666Tyr, p. Asn666Ser, and p. Asn666His, lead to a variety of health issues. These
Bladder cancer is a serious health issue. It affects many people worldwide. The role of hepatocyte growth factor activator inhibitors (HAI-1 and HAI-2) in this type of cancer is not fully understood. However, recent studies have shed some light on their potential. In earlier research, it was fou
There is a protein called TAK1. It plays a big role in many cell activities. But its part in cancer spread is not fully known. Researchers have found that when TAK1 is reduced, a type of throat cancer, called esophageal squamous cancer, spreads faster. This happens both in lab dishes and in live mic
Scientists have been tinkering with molecules to create new tools to battle cancer. They started with a bunch of compounds called diethyl α-amino-α-aryl-methylphosphonates. These compounds were then mixed with different chemicals to create new versions. The process involved using phosphoryl chloride
Peek into the inner workings of cells, and you'll spot a process called phosphorylation. It's like a tiny light switch that can turn proteins on and off, or rather, it changes their shape, changing their behavior. Knowing when and where this happens is crucial for understanding illnesses and how cel
Ever wondered how proteins interact in our cells? Let's dive into the relationship between MAP2c and 14-3-3ζ. MAP2c, a protein that hangs out near microtubules, gets cozy with 14-3-3ζ in a special way. This meeting depends on a process called PKA phosphorylation. Scientists used various tools like c
Mitochondria are like tiny power plants inside our cells. They make most of the energy our cells need, called ATP, through a process called oxidative phosphorylation. This process uses the electron transport chain (ETC) to pump protons and create an energy gradient, which is then used to make ATP. H
