In the world of medicine, antibodies are like superheroes. They can target and fight specific diseases. But to make them even more effective, scientists often need to attach other molecules to them. This is where the concept of site-selective antibody labeling comes into play. The process involves modifying antibodies at specific points. One such point is Lys248 on ...

Macrophages, the body's cleanup crew, swallow dead cells through a process called efferocytosis. During this cleanup, they make special lipid molecules using oxygenases. Among these, very reactive lipid-derived electrophiles (LDEs) can modify important proteins inside the cells. But until now, we didn't know much about how these LDEs work. Scientists did experiments...