Long-acting growth hormone (LAGH) therapy is changing the game for people with growth hormone deficiency (GHD). It's a big step forward because it means fewer injections and better treatment adherence. In Germany, three LAGH products have hit the market: lonapegsomatropin, somapacitan, and somatrogon. The INSIGHTS-GHT registry is tracking how these are being used in...
Real-world evidence (RWE) is becoming a big deal in the world of medicine. It's used to back up the effectiveness of new drugs and treatments. But how exactly does it influence decisions made by regulatory bodies and health tech assessors? This is a tricky question. To find out, a special tool called FRAME was created. FRAME stands for Framework for Real-world eviden...
Atopic dermatitis, or eczema, is a skin condition that can cause a lot of discomfort. It is not just a skin issue. It might also affect other parts of the body. One surprising connection is with the mouth. People with atopic dermatitis may face a higher risk of periodontitis. This is a serious gum disease. It can lead to tooth loss if not treated properly. So, what ...
Psoriasis is a long-term skin condition that affects a significant number of people worldwide. Around 2-3% of the global population deals with this issue. Over the years, various treatments have been developed to manage and reduce the symptoms of psoriasis. These treatments have led to notable improvements, often measured by the Psoriasis Area Severity Index (PASI). ...
Chronic migraines are a real pain, literally. They can last for weeks or even months. People who suffer from them often try different treatments to find relief. One study looked at combining two treatments: atogepant and onabotulinumtoxinA. The goal was to see if this combo could help control chronic migraines better than using either treatment alone. The study was ...
Let's talk about intraocular inflammation (IOI) and its link to faricimab therapy. This medication is used to treat eye conditions, but like any treatment, it can have side effects. So, what did we learn from observing patients over a year in a big hospital? Researchers wanted to get real-world insights into how common IOI was and how severe it could get. They found...