Cryo-electron microscopy (cryo-EM) has changed the game in studying tiny structures. It's faster and can handle bigger samples than before. But there's a catch: getting the samples ready is still tricky. The ice thickness can be uneven. Particles might stick to the support or line up in the same direction. This can make it hard to get clear, high-resolution images. ...

Styrene monooxygenases are special enzymes that can tell the difference between left and right-handed molecules. These are known as enantiomers. They are part of a bigger family called Group E flavoprotein monooxygenases, or GEMs. These enzymes are great at making one enantiomer more than the other in a reaction. However, figuring out how to control which enantiomer...