In science, experiments that test how chemicals affect living things are essential for protecting the planet. Yet many studies leave out important details, making it hard to repeat or reuse their results. Because collecting data in labs or on farms is expensive, researchers often cut corners when
In a recent study, scientists dug deep into how a common environmental chemical, monoethyl phthalate, might be connected to thyroid cancer. This chemical is everywhere, and researchers wanted to figure out how it might be triggering cancer at a molecular level. First, they gathered a list of genes
Creating new drugs is tough and expensive. Right now, scientists use flat cells or animals to test drugs, but these methods don't always work well for humans. That's where new tech comes in: tiny, 3D versions of human organs, called organoids, and special chips that mimic how organs work. These tool
Forensic science is getting a makeover, and it's all thanks to something as small as a drop of blood. Dried Blood Spot (DBS) cards are becoming the talk of the town, especially in toxicology. These little cards are not just easy to use but also super efficient. Scientists have been working hard to m
Coastal areas often bear the brunt of human activities, with pollutants seeping into the water and settling into the sediments. Among the creatures affected are golden kelp, E. radiata, which can't just up and leave when things get tough. They have to toughen up or adapt to survive. Scientists want
PFAS, or per- and polyfluoroalkyl substances, have become a hot topic in research lately. Scientists are digging deep to understand how these chemicals affect our health. They are found almost everywhere, from the food we eat to the water we drink, even in the air we breathe. These chemicals can sne
In the heart of Brazil's Ceará coast, the Cocó River tells a story of urban life's hidden impact. This river, surrounded by bustling cities, is a hotspot for various pollutants. Scientists dove deep into this issue, checking water, sediment, and even the creatures living there. They found a shocking
When someone gets hurt or commits a crime, figuring out what drugs they took can be crucial. Usually, experts look for drugs in blood or other body fluids. But what if those aren't available? That's where things get tricky. Sometimes, the only clues left are on clothes, bedding, or other items. The
The world of toxicology is changing. Researchers have been exploring new ways to test how harmful substances affect living things. One exciting development is the use of three-dimensional (3D) cell cultures. These 3D models are better at mimicking real tissues than the old flat (2D) cell layers.
Japan has a rich history in the realm of drug metabolism and disposition. This is clear when looking at the contributions made by Japanese researchers to the journal Drug Metabolism and Disposition over the last 50 years. Their work has significantly shaped the field, focusing on drug metabolism, me
