Triple negative breast cancer (TNBC) is a challenging type of breast cancer. It's tough to treat because it doesn't respond well to targeted therapies. This is partly due to changes in certain signaling pathways, like the PI3K and mTOR pathways. Researchers have found that a protein called RICTOR plays a big role. When RICTOR is overactive, it makes TNBC mor...
Imagine the frustration of wanting to start a family but being held back by infertility. This is a reality for many couples in the U. S. where about one in seven couples face this challenge. In vitro fertilization (IVF) can be a solution, but it comes at a high cost. We're talking $12, 000 to $25, 000 per cycle. That's a lot of money for something that might not work...
Knee issues are a big deal. And there is a noticeable change in how doctors are handling them. In the past, doctors would try to fix broken bones around the knee using other methods. But nowadays, there is a growing trend toward primary total knee arthroplasty (TKA). This is a fancy term for replacing the whole knee joint. The European Knee Society (EKS) is a group ...
Imagine this. We live in a country where liver problems, specifically a condition called MASH, are on the rise. MASH is a nasty companion of unhealthy lifestyles, and it's becoming a major headache for doctors who specialize in stomach and liver issues. You might be wondering, "What's the big deal? " Well, MASH can lead to some serious complications like scare back l...
Shoulder pain can be a real bummer. One common type is subacromial pain syndrome (SAPS). There are lots of treatments out there, but they all have small to moderate effects. This means it can be tough for patients and healthcare providers to pick the best one. A recent study wanted to find out what patients with SAPS really need when deciding on treatments. The goal ...
Ever heard of endometriosis? It's a sneaky condition where uterine tissue decides to grow outside the uterus. While it's common, it can cause major pain and make getting pregnant tough. So, let's dive into what's new in diagnosing and treating this issue. Docs are always on the lookout for ways to spot endometriosis early. Laparoscopy is one method, but it's invasiv...
Metastatic breast cancer is serious business. It's when cancer spreads from the breast to other parts of the body. There are two main types: hormone receptor-positive (HR+) and triple-negative (TN). For a long time, chemotherapy (CT) has been the standard treatment. But now, antibody-drug conjugates (ADCs) are grabbing attention. These are like smart bombs that targe...
Imagine you're a doctor trying to diagnose a young, previously healthy adult with strange symptoms like swollen lymph nodes and inflammation. This could be a sign of something called Castleman disease, a rare condition where the immune system goes haywire. One type, called idiopathic multicentric Castleman disease or iMCD, is especially tricky to spot because its sym...
La La Anthony, a well-known figure in entertainment, opened up about her struggle with plaque psoriasis, an autoimmune disease that causes irritated skin patches. Despite her high-profile career, she's dealt with this condition for years. While there's no cure, treatments can help manage symptoms. Amgen partnered with La La to raise awareness and encourage open conve...