Pregabalin is a drug that has gained attention for the wrong reasons. It is typically prescribed to manage epilepsy, nerve pain, and anxiety. However, its calming and euphoric effects have led some people to misuse it. This misuse is becoming a bigger problem, especially in areas where traditional drug issues have been tackled. A recent incident involving a 20-year-o...
MAC-PD (Mycobacterium avium complex pulmonary disease) is a big challenge for doctors and patients alike. The usual treatments don't always work well, and they can cause nasty side effects. This makes it hard for patients to finish their treatment as planned. When someone shows up with long-lasting breathing problems that might be caused by NTM (nontuberculo...
Ever thought that your belly could be chatting with your brain? Well, our instincts matter, and Its being discovered very important. Recently, scientists have been making some cool discoveries about some serious conditions: anorexia nervosa and depression. Science is realizing that our intestines, the ones with all those important bacteria, have an endless debate to...
Cancer in the stomach and esophagus has been tough to beat, but new treatments are changing that. Still, these cancers cause unique nutrition problems. Before, during, and after treatments, patients have special needs. This is where nutrition steps in, becoming a crucial part of their care. Doctors and nutritionists work together to make sure patients get the right ...
Digital therapeutics, or DTx, is a hot topic in the scientific world, drawing attention from all over. This review dives into what DTx is and how it can help treat various diseases, comparing it to traditional drug treatments. It also looks at the good and bad parts of the current European laws on DTx. DTx is like a new tool in the healthcare toolbox. It uses digita...
Cancer cells have a sneaky way of hiding from our immune system. One of their tricks involves a molecule called human leukocyte antigen G, or HLA-G for short. Normally, HLA-G helps keep the immune system from attacking our own bodies. But in cancer, this molecule goes rogue. It creates a sort of invisible shield around the tumor, making it hard for immune cells to sp...
Did you know your liver health can affect your heart? Let's dive into metabolic dysfunction-associated steatotic liver disease, or MASLD for short. It's the most common chronic liver condition, where fat builds up in the liver, along with at least one cardiometabolic risk factor. People with MASLD face higher chances of heart problems. But why does liver health matt...
Ever thought about how diabetes can mess with your brain? It's true, and it's a big deal. Diabetes can cause something called cognitive impairment, which basically means your brain doesn't work as well as it should. This can make everyday life tough. So, what's going on? Well, scientists think it has to do with how diabetes affects your body. It can mess up your blo...
Macrophages, often called TAMs (tumor-associated macrophages), are crucial immune cells hanging out in the tumor's neighborhood, or what we call the tumor microenvironment. In cervical cancer, they play a big role. They can either help the cancer grow, spread, and find new blood vessels, or they can slow the cancer down. Researchers are trying to understand how these...
IgG4-related disease (IgG4-RD) is a curious immune condition. It makes certain organs swell and not work properly. One big clue is that affected organs grow special lymphoid tissues, called TLTs. Inside these, special helper T cells (Tfh2) turn regular B cells into IgG4+ cells, which cause the swelling. These helper cells also make important cytokines, IL-4 and IL-10...