Accurately estimating the future sales of drugs that are already on the market, known as post-revenue assets, is a big deal in the pharmaceutical world. It helps companies like Pfizer make smart decisions about where to invest their money. This study introduces a new way to forecast these sales by u
When iron and carbon alloys transform, things can get complicated. Sometimes, the growing ferrite and austenite phases, instead of working together, drift apart due to pre-existing cementite particles in the austenite phase. This is what's called a non-cooperative or divorced eutectoid transformatio
As winter approaches, Iran is facing rolling blackouts, leaving people and businesses in the dark. The country’s energy woes are a blend of many factors, including economic mismanagement, international sanctions, and, perhaps surprisingly, a cryptocurrency boom. Bitcoin mining, which demands vast am
Imagine a hidden battle playing out in the rivers of Curitiba, Brazil. The culprits? Three drugs—azithromycin, ivermectin, and hydroxychloroquine—used widely during the COVID-19 pandemic. Scientists dove into this issue, finding alarming levels of these medicines in both water and sediment from urba
The Heliophila plant family, with over 100 species, is the most diverse in the Brassicaceae lineage. It's mostly found in southern Africa, near two biodiversity hotspots. A close relative, Chamira, has a unique trait: it keeps its seed leaves. Researchers found a big genome change, like a duplicatio
This week, President Xi Jinping of China indicated that Beijing is ready to work with the incoming U. S. President, Donald Trump, to resolve trade disputes. In a letter to a U. S. -China business council, Xi underlined the importance of choosing dialogue over conflicts and cooperation over competiti
Have you ever wondered why some people can hear through their bones? This fascinating phenomenon is called bone conduction (BC) hearing. Scientists used a special model of the human head to study how the direction and timing of forces impact this unique way of hearing. They created various force di
Picture this: about 50, 000 years ago, humans and Neanderthals started mixing. This genetic exchange lasted for around 7, 000 years. Today, non-African humans carry about 1% to 2% Neanderthal DNA. This blend might have strengthened our immune systems and influenced our skin colors. But not all Neand
Purifying large biotherapeutic entities like viral coat proteins and mRNA is tougher than handling smaller products. These huge molecules struggle to reach binding sites in regular chromatographic media. However, size exclusion chromatography (SEC) offers a potential solution by isolating them in th
In a recent twist of events, New York's governor has openly called on President Biden to take swift action against the mysterious drones that have been causing disruptions. The drones, which have been spotted flying over sensitive areas, have led to the temporary shutdown of a major airfield. The go
