A man from New Jersey passed away from a severe lung cancer that doctors suspect might be linked to his long-term use of e-cigarettes. This case is believed to be the first of its kind, raising serious questions about the safety of vaping.

The man, who was 51 years old, had been vaping for over a decade after quitting traditional cigarettes in 2009. He first sought medical help in 2020 when he started experiencing chest pain, difficulty breathing, weight loss, and coughing up blood. Doctors found a large tumor in his left lung, about the size of a pack of cards. This type of cancer is typically seen in heavy smokers, but his last chest scan just two years earlier had been clear, leading doctors to consider vaping as a possible factor.

The tumor had spread to the tissue around his heart, making surgery impossible. He began chemotherapy, but the cancer progressed quickly, and he died just three months after his diagnosis. The case, detailed in a medical report, suggests a potential link between vaping and cancer in humans, although previous studies had only shown this in lab animals.

Doctors from the medical center where he was treated noted that while they couldn't prove causation, the case highlights a potential connection between e-cigarette use and cancer. They called for more research to understand the long-term effects of vaping and its role in lung cancer development.

The man's case is particularly concerning because he was relatively young and had quit smoking traditional cigarettes over a decade before turning to vaping. His rapid decline and lack of response to chemotherapy suggest a more aggressive form of cancer, possibly influenced by his prolonged use of e-cigarettes.

E-cigarettes work by heating a liquid that contains nicotine, flavorings, and a mix of toxic chemicals. When inhaled, this vapor can deliver harmful substances deep into the lungs, including chemicals known to cause cancer. Over time, this damage can lead to DNA mutations and inflammation, increasing the risk of cancer.

The man's tumor was a type of lung cancer called squamous cell carcinoma (SSC), which accounts for about 20 to 30 percent of all lung cancer diagnoses in the US. SCC is often called a "silent killer" because it may not cause obvious symptoms in its early stages. When symptoms do appear, they are often mistaken for less serious conditions. Early detection of SCC has a five-year survival rate of around 50 percent, but this drops to just seven percent once it spreads beyond the lungs.

The man was initially sent home after his diagnosis, with plans to start treatment as an outpatient. However, within two weeks, he returned to the hospital in severe pain. The tumor had grown so large that it was compressing his airways and making it hard to breathe. Doctors inserted a stent to help open his lungs, and he was prescribed radiation and chemotherapy. Despite these efforts, the cancer continued to spread, and he died within two months.

Doctors are now urging more research into the cancer risks associated with e-cigarette use, especially as more long-term users age into the typical cancer window. They also suggest updating cancer screening criteria to include chronic vapers, particularly those with over a decade of use. Early detection could lead to timely intervention and better outcomes.

Vaping has become increasingly popular, especially among young adults. An estimated 16 million American adults currently use e-cigarettes, with the highest rates seen in young adults aged 18 to 24. Among children, about 1. 6 million middle and high school students still vape, though usage has declined since its peak in 2019.

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