Cancer treatment has seen big improvements with targeted therapies and immunotherapy. Yet, getting drugs to work effectively inside the body remains a hurdle. One key way cells absorb drugs is through endocytosis, a process where cells bring in substances from their surroundings. Scientists are now focusing on this process to make drug delivery more efficient. Tumor...
Cancer treatments are harsh, and chemotherapy side effects can be overwhelming. But what if our diet could lend a helping hand in the battle against cancer? This idea is now under the microscope. Our gut is home to trillions of tiny organisms that influence our health. Scientists are investigating if these microbes can aid cancer patients. They're experimenting with...
Novartis, a Swiss pharmaceutical giant, has just opened a new manufacturing plant in Carlsbad, California. This facility is part of a bigger plan to invest $23 billion in the United States over the next five years. The focus of this new plant is on making cancer drugs, specifically for a treatment called radioligand therapy (RLT). RLT is a type of precision medicine ...
NK cells are like the body's first line of defense against cancer. They can spot and attack harmful cells without needing a specific signal. This makes them a promising tool for fighting cancer. However, tumors can create a tough environment that weakens NK cells. This environment can make it hard for NK cells to do their job. Scientists are studying how NK cells ada...
In the world of cancer treatment, new methods are always being explored. One such method is HIPEC, which involves delivering heated chemotherapy directly into the abdomen during surgery. But with this treatment, a big question arises: which chemotherapy drug is safer when used in high doses? Two drugs often used in HIPEC are mitomycin C and oxaliplatin. Previous res...
Colon cancer is a serious disease that takes many lives. Scientists have found that a protein called B7-H4 is more active in colon cancer cells than in healthy cells. This protein helps cancer cells grow. So far, no medicines have been made to target B7-H4 in colon cancer treatment. Researchers set out to create a special kind of antibody, called a trispecific antib...
In Japan, doctors have a tough job. They must navigate between treatments covered by public health insurance and costly private options that lack solid evidence. These expensive treatments, referred to as "X" in a recent study, have sparked a debate among oncologists. Over 6, 000 oncologists were surveyed about their opinions on X. Although only 13% responded, the s...
The COVID-19 mRNA vaccines, which played a big role in saving lives during the pandemic, might also have a surprising benefit: helping the immune system fight cancer. This idea came from a study that looked at how these vaccines affect patients with certain types of cancer. The study focused on patients with late-stage melanoma and lung cancer who were receiving a t...
CDR404, a new type of cancer treatment, is making waves in the medical world. This treatment is designed to target specific cancer cells and activate the body's immune system to fight them. Recent studies have shown that CDR404 can trigger a strong immune response in patients with certain types of cancer, including ovarian cancer and synovial sarcoma. The way CDR404...
Zymeworks, a biotech company, has shared positive early results from its phase 1 trial. The trial is for a new drug called ZW-191. This drug is designed to target a specific marker called folate receptor-alpha (FRα) found in many cancer types. The results show that ZW-191 can shrink tumors and is generally safe for patients. The trial included patients who had tried...