IgG4-related disease (IgG4-RD) is a curious immune condition. It makes certain organs swell and not work properly. One big clue is that affected organs grow special lymphoid tissues, called TLTs. Inside these, special helper T cells (Tfh2) turn regular B cells into IgG4+ cells, which cause the swell
Medicines used to treat and prevent heart thrombosis have truly changed the game. They've made a big difference in how patients with heart artery disease do, but they've also made it trickier for doctors to decide on the best treatment. With improved ways to fix heart arteries and better stents, the
You probably know that medications can sometimes have side effects. But do you know about nitrosamines? These are harmful chemicals that can form in drugs. They're not something we want in our medicine. Let's dive into why they're a problem and how we're trying to deal with them. In 2019, some medi
Researchers have come up with a smart new way to figure out how much coastal cliffs are eroding. They combined data from drones, satellites, and laser measurements to see how bad the erosion is. This method helps us understand both natural wear and tear on cliffs and damage to protective structures
Follicular lymphoma (FL) can be a tricky disease. Sometimes, it worsens quickly, within just two years. This is called progression of disease within 24 months (POD24), and it can really affect how long patients live. A group of researchers from China decided to tackle this problem. They wanted to fi
Immuno-oncology drugs, like immune checkpoint inhibitors (ICIs), have shown potential in treating various cancers. For advanced non-small cell lung cancer (NSCLC) patients with PD-L1 expression of 50% or higher, single-drug ICI therapy that targets PD-L1 is the standard treatment. But can machine le
Healthcare fraud is a massive problem worldwide, sucking up billions of dollars each year. Experts have taken up the challenge using machine learning. They started by cleaning and preparing massive amounts of data for analysis. Next, they experimented with various models, picking the best ones for t
These days, biomedical research and healthcare are getting a major boost from digital health technology (DHT). New tech, clever uses of old tech with AI and machine learning, and better data integration are making DHTs super useful. But how well are these tools being funded? A study dived into the N
Football players often get injured without any contact. Most studies look back at these injuries and focus on GPS data. But injuries happen because of many reasons, not just one. This study used machine learning to predict these injuries. It looked at GPS data and other player details from a Portugu
Cytotoxic T lymphocytes (CTLs) are crucial for fighting cancer, but many people with liver cancer (HCC) who have lots of these cells still face early relapse or resistance to treatments. Scientists don't fully understand why this happens. They studied 20 patients with liver cancer and CTLs to figure
