ALKBH5, a protein that removes a specific chemical tag from RNA, is known to make head and neck squamous cell carcinoma (HNSCC) more aggressive. But how exactly it does this has been a mystery. Now, researchers have uncovered a new pathway involving ALKBH5, a long non-coding RNA called NEAT1, and tw
In the world of gut health, a tiny protein named Amuc_0904 is making big waves. This protein, found in a beneficial gut bacterium called Akkermansia muciniphila, plays a crucial role in healing our intestines. When our gut is inflamed, like during colitis, this protein steps in to help. It boosts th
Lung neuroendocrine neoplasms, or NENs, are not a single type of tumor but a group of different ones. This group includes well-differentiated neuroendocrine tumors (NETs) and neuroendocrine carcinomas (NECs). Even though doctors have known about these tumors for a long time, they still find them tri
Gastrointestinal stromal tumors, or GISTs, are a type of tumor that can grow in the digestive system. These tumors can occur in both dogs and humans. They are often linked to changes, or mutations, in a gene called KIT. Scientists took samples from 55 cases of canine GISTs. They looked for spec
Preeclampsia is a serious pregnancy complication. It affects how the placenta grows and functions. One key player in this drama is a molecule called TET3. This molecule has been linked to problems with the cells that make up the placenta, known as trophoblasts. When these cells don't work right, pre
Cells are the building blocks of life, and their growth is crucial for an organism's survival. This growth depends on a mix of metabolic processes, available nutrients, and signaling pathways. One key player in this process is an enzyme called CTPS. It is vital for making nucleotides, the building b
In the world of science, certain gatherings stand out for their impact. One such event is the Molecular Mechanisms of Immune Cell Development and Function (MMICDF) meeting. This event is unique. It is held every two years. It focuses on the tiny building blocks that drive our immune system. The
Plants have a clever way of defending themselves against invaders. They use special receptors on their cell surfaces to spot trouble. These receptors can pick up signals from both the bad guys (pathogens) and helpful peptides released by the plant itself. This is like having a security system that c
Imagine doing something as complex as DNA extraction without needing a lab full of expensive equipment. That's what some researchers have managed to do. They've found a way to extract DNA using simple household items, making the process faster, cheaper, and more environmentally friendly.
Ever wondered why some plant DNA extraction kits give you better results than others? It all comes down to how well they handle the DNA, especially for those tiny little plants. Scientists use these kits to study the genetic material of plants, and the quality of the DNA they get can make or break t
