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Dec 27 2024SCIENCE

Discovering Violaceoid F: A New Way to Fight Cancer Cells

Ever wondered how some compounds can help fight cancer? Let's talk about violaceoid F, a small molecule that's making big waves in cancer research. It all starts with FOXO3a, a protein that keeps cells from growing too much and triggers cell death when needed. In cancer cells, FOXO3a likes to hang o

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Dec 27 2024HEALTH

The Journey of ASOPRS Fellows: Careers and Contributions

Ever wondered what happens to those who complete the American Society of Ophthalmic Plastic and Reconstructive Surgery (ASOPRS) fellowship? Let's dive into the career paths and societal contributions of these graduates from 2000 to 2021. First off, where do these surgeons end up practicing? It turn

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Dec 26 2024SCIENCE

How Phosphorus Boosts Nickel-Iron's Oxygen Evolution

Scientists have long known that nickel-iron catalysts are great at producing oxygen from water, especially in alkaline conditions. But how they do it so well was a mystery—until now. A recent study looked at a special catalyst, nickel-iron phosphide (NiFeP), which is super active and stable. It only

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Dec 25 2024HEALTH

Understanding and Managing Complicated Bacterial Infections in the Blood and Heart

Gram-positive bacteria, like Staphylococcus aureus, Streptococcus, and Enterococcus, are commonly behind bloodstream infections and heart inflammations. "Complicated bacteremia" is a term doctors use for S. aureus infections that spread to other parts of the body. This requires longer treatment and

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Dec 25 2024HEALTH

Why Biliary Tract Cancer is Often Caught Late

Biliary tract cancer, or BTC, starts in the bile ducts inside the liver (intrahepatic cholangiocarcinoma), the main ducts near the liver (extrahepatic cholangiocarcinoma), or the gallbladder (gallbladder cancer). Because symptoms are often vague and there are no routine screenings, most patients don

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Dec 24 2024HEALTH

TriFocal Lens: Seeing Near, Far, and In-Between

Everyone dreams of perfect vision. But what if a lens that promises just that also comes with some downsides? Let's talk about the PanOptix trifocal intraocular lens (IOL), which is designed to give clear vision at all distances — near, intermediate, and far. It's great for tasks like reading, worki

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Dec 24 2024SCIENCE

From Einthoven's Discovery to Modern Heart Health: A Century of Progress

A hundred years ago, Willem Einthoven changed the way we understand our hearts. He was awarded the Nobel Prize for figuring out how to read the heart's electrical signals, a process we now call electrocardiography. This method lets us see the heart's activity on the body's surface, which is pretty a

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Dec 24 2024SCIENCE

Transforming MoS2 Clusters for Better Biocatalytic Action

MoS2 is a widely available material with a stable structure, adjustable energy gap, and easy shear properties. These features make it valuable in fields like catalysis and biomedicine. However, its biocatalytic activity needs improvement for practical use in biomedicine. In this study, scientists cr

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Dec 24 2024SCIENCE

Unleashing the Power of Chiral Phosphorus: A New Way to Make Complex Molecules

Imagine trying to build a complex, three-dimensional structure using specific building blocks. That's what scientists do when they create chiral phosphorus compounds. These molecules have a specific shape, much like a left or right hand. Although methods to craft these structures exist, their true p

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Dec 23 2024SCIENCE

Discovering the Power of Earth-Friendly Metals for Hydrogen Production

Hydrogen evolution reaction (HER) is vital for generating hydrogen fuel through water splitting. To make this process sustainable, researchers are searching for abundant materials like silicates. A recent study synthesized various metal metasilicates using a simple wet-chemical method followed by hi

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