PASE

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Apr 23 2025SCIENCE

The Evolution of PI4P: From Obscurity to Versatility

PI4P, or phosphatidylinositol 4-phosphate, is a lipid that has gained significant attention in the world of cellular biology. It was once overshadowed by its more famous relatives, DPI and TPI. These were initially discovered due to their rapid turnover rates, which scientists observed through a tec

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Apr 12 2025SCIENCE

Apple Roots and the Iron Puzzle

Iron is a big deal for plants. It is crucial for many processes. These include breathing, making chlorophyll, and helping with photosynthesis. When plants don't get enough iron, their roots have to work harder. This is where a special enzyme comes in. It is called H+ -ATPase. This enzyme helps lower

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Mar 11 2025SCIENCE

Miniature Fluorescent Tools Shed Light on Cancer and Brain Health

Picture this: tiny, glowing tools that can help us understand and treat diseases like cancer and brain disorders. These tools are called miniaturized fluorescent probes, and they are designed to target a specific enzyme called monoacylglycerol lipase (MAGL). MAGL is crucial because it helps control

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Jan 30 2025SCIENCE

Hagfish: The Bridge Between Invertebrates and Vertebrates

Ever wondered how hagfish digest their food and their role in the evolution of vertebrates? These creatures have an unusual digestive process. Their gut fluid is acidified like that of many invertebrates. This process is carried out by a mechanism called the vesicular-type H+-ATPase, or VHA for sho

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Dec 14 2024HEALTH

Uncovering a New Weapon Against Alzheimer's: The Hunt for Caspase-6 Inhibitors

Caspase-6, a protein linked to brain cell death and neurodegeneration, has been on scientists’ radar for a while. This protein is especially active during inflammation and may play a role in the early stages of Alzheimer's disease. Researchers have now combined two drug-designing approaches to find

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Dec 13 2024HEALTH

The Power of Hertia Leaves: A Natural Weapon Against Obesity

For ages, people have used the leaves of the Hertia cheirifolia L. plant to treat various health issues like hemorrhoids, diarrhea, and stomachaches. Scientists have now found a new use for these leaves: helping fight obesity. They extracted the aerial parts of the plant using hexane after hydroalco

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