Multiple sclerosis (MS) is a tricky disease that affects the brain and spinal cord. It's like a puzzle with many pieces, and one of those pieces might be the bacteria living in our guts. These tiny organisms, known as gut microbiota, play a big role in how our bodies handle fats, like cholesterol and fatty acids. Researchers are digging deep to understand how gut ba...
Cancer treatment has seen big improvements with targeted therapies and immunotherapy. Yet, getting drugs to work effectively inside the body remains a hurdle. One key way cells absorb drugs is through endocytosis, a process where cells bring in substances from their surroundings. Scientists are now focusing on this process to make drug delivery more efficient. Tumor...
Aging is a big deal, and not just because of wrinkles. It's about how our cells change and talk to each other. Once, scientists thought senescent cells, which are like old, grumpy cells that stop dividing, just hung out in one place. But now, they know these cells chat with other cells all over the body. They send out signals, like tiny messages in a bottle, that can...
Cancer is a major health issue worldwide, causing many deaths and illnesses. Even with progress in treatment, there are still big hurdles to overcome. This is why scientists are always looking for new ways to fight cancer. One exciting area of research is m5C RNA methylation. This process involves adding a methyl group to cytosine, one of the building blocks of R...
Alcohol's effects on blood pressure aren't the same for everyone. They vary between men and women. This is because of differences in how alcohol is processed in the body and how blood pressure is controlled. Understanding these differences is crucial for developing effective treatments. The way alcohol is broken down in the body plays a big role in how it affects...
The liver is a tough organ. It can handle a lot of damage. However, when the liver is hurt over and over, it starts to scar. This scarring is called fibrosis. It is a big problem. It can lead to serious issues like cirrhosis and even liver cancer. But here is the good news. Fibrosis can be reversed. This means that finding ways to stop or even fix liver scarr...
The heart is a powerful organ, but it can be vulnerable to serious issues. One such problem is coronary artery spasm (CAS). This condition is tough to treat, but there's hope on the horizon. Researchers have been exploring the use of traditional herbal remedies to tackle this issue. At the heart of this research is the Xiao-Xu-Ming decoction. This ancient herbal...
Cells have clever ways to handle stress. They use special proteins to manage changes inside and outside the cell. These proteins, known as lysine acetyltransferases (KATs) and deacetyltransferases (KDACs), play a big role in how cells react to stress. They do this by adding or removing tiny chemical tags, called acetyl groups, on other proteins. This process, called ...
Breast cancer is the most common cancer affecting women worldwide. It puts a huge strain on both individual health and healthcare systems. At the heart of this disease are breast cancer stem cells (BCSCs). These cells have special abilities. They can renew themselves, turn into different types of cells, and resist standard treatments. This makes them crucial in the s...
Diabetes is a complex condition that often brings along unwanted guests, like pain. This pain can be tough to manage because it's not just about what's happening in the body, but also in the brain. One key player in this brain-body connection is the acid-sensing ion channel 1a, or ASIC1a. This tiny channel has a big job in how the brain processes pain signals. In th...