Two new drugs, lecanemab and donanemab, have hit the market. They are designed to tackle Alzheimer's disease. They work by targeting and removing beta-amyloid protein from the brain. This protein is a key player in the development of Alzheimer's. The drugs have shown some promising results in clinical trials. They improved scores on cognitive and functional test...
Alzheimer's disease is a big deal. It's a condition where the brain slowly breaks down. It's one of the toughest medical puzzles out there. Scientists have found that certain gene mutations can lead to early-onset Alzheimer's. These mutations are in the presenilin 1 and 2 (PSEN1 and PSEN2) and the amyloid precursor protein (APP) genes. These genes are crucial for the...
Ruth Buzzi, a name that might not ring a bell for many, was a powerhouse of comedy. She was known for her role as the purse-wielding Gladys on "Rowan & Martin's Laugh-In. " This show was a wild mix of comedy sketches that perfectly captured the spirit of the 1960s. Buzzi passed away at her ranch near Fort Worth at the age of 88. Her death was due to complications fro...
Alzheimer's disease, or AD, is a tough nut to crack. It's a brain disorder that slowly chips away at a person's memory and thinking skills. It's tricky because it affects different people in different ways. But here's where things get interesting. Scientists have been using something called single-cell sequencing. This tech is like a super-powered microscope that let...
Understanding the brain's inner workings is like solving a massive puzzle. One piece of this puzzle is a protein called APP. For a long time, scientists have focused on a part of APP that floats outside cells, known as Aβ. This part has been linked to the loss of connections between brain cells in Alzheimer's disease. However, there's more to the story. Inside cells,...
In the world of brain health, Alzheimer's disease is a major concern. It is a condition that slowly damages the brain. It is linked to problems with stress hormones and the body's stress response system. This system is called the HPA axis. The HPA axis is a network of interactions between the hypothalamus, pituitary gland, and adrenal glands. It plays a crucial ...
Alzheimer's disease brings many struggles, especially with memory loss and feeling lonely. Toys and games can help people with Alzheimer's feel better. They can bring happiness and make people want to connect with others. However, not many toys are made just for them. A recent effort looked into how to make special toys for people with Alzheimer's. It wanted to ...
Alzheimer's disease is a scary prospect for many. It's a condition that affects memory and thinking skills. One group of people who are at high risk are those with a specific genetic mutation. This mutation is known as the Presenilin-1 E280A mutation. It is found in a large family in Colombia. This mutation causes a type of Alzheimer's that runs in families. It is c...
Alzheimer’s disease is a complex condition that has long been challenging to diagnose and track. However, a groundbreaking development in medical science offers new hope. Researchers have found a way to detect and monitor Alzheimer’s using a straightforward blood test. This innovation could transform how doctors approach Alzheimer’s care, making it more accessible an...
Alzheimer's disease is a serious issue worldwide. It is marked by a buildup of amyloid-β plaques, tangled proteins, brain inflammation, and a steady decline in mental abilities. Luckily, there is hope in the form of dietary polyphenols. These compounds found in many foods might help lower the risk and slow down the progression of Alzheimer's. They work in several way...