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Jan 08 2025HEALTH

Improving Ovarian Cancer Treatment with Immune Checkpoint Inhibitors

Treatment options for epithelial ovarian cancer (EOC) have expanded a lot in recent years, but much of the progress has been tied to picking the right biomarkers. This means there's still a big need for better treatment options to help patients live longer and enjoy better quality of life. Unlike ma

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Jan 08 2025HEALTH

Red Flags in Newly Diagnosed Ovarian Cancer: A Closer Look at Immune Response

When cancer spreads, it tends to twist the environment around it. In metastatic epithelial ovarian cancer (EOC), normal neutrophils, which usually help fight infections, get tricked into becoming "suppressors. " These reprogrammed neutrophils can hinder the activation of T cells, a vital part of our

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Jan 07 2025HEALTH

Creating an Islamic Medical Guide: Malaysia's Unique Approach

In today's diverse healthcare world, meeting the specific needs of Muslim patients is more important than ever. However, without clear guidelines, healthcare professionals often face difficulties in providing care that aligns with Islamic values. To solve this, experts in Malaysia are developing a n

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Jan 07 2025SCIENCE

The Mystery of Different Y-Chromosome Branch Lengths

The Y chromosome, which doesn't recombine, holds vital clues about paternal human history. Scientists have noticed something puzzling: some Y chromosome branches are much longer than others, especially those that are very different from the standard human Y chromosome. This length variation isn't ex

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Jan 06 2025HEALTH

Unraveling the Mysteries of KCNQ2 Encephalopathy in Kids

Kids with brain development issues caused by KCNQ2 variants face a tough time getting diagnosed. This is because these variants are quite diverse and their effects aren't clear. Let's take a look at one child who had seizures right after birth, along with moderate brain development problems. This ch

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Jan 06 2025POLITICS

Military's Role in Protecting Civilians: Shifting Gears

For a long time, the protection of civilians (POC) in conflict wasn't a big deal in military strategies. It was more about arms bearers following international humanitarian law (IHL). But things are changing. The nature of conflicts is transforming, with more internal fights happening in cities by u

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Jan 06 2025HEALTH

How COVID Variants Delta and Omicron Latch On: A Closer Look

The COVID-19 pandemic has been a global challenge. Two variants, Delta and Omicron, have raised eyebrows due to their potential to spread more easily and dodge our immune system. This study used computer simulations to understand how these variants interact with a key receptor in our body, called AC

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Jan 05 2025HEALTH

How Bariatric Surgery Trials Report Lifestyle and Nutritional Details

Ever wondered how well bariatric surgery trials report the nitty-gritty details of perioperative lifestyle and nutritional interventions? A recent study took a close look at this, using the TIDieR checklist as a guideline. The TIDieR checklist is like a check-up list for clinical trials, ensuring al

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Jan 05 2025HEALTH

Does Donor Age or Sex Really Matter in Osteochondral Allograft Transplants?

You might have heard that mismatches between osteochondral allograft (OCA) donors and recipients can lead to not-so-great results. But what about other donor factors like age or sex? A recent study took a closer look at these variables and their impact on important outcomes, reoperations, and failur

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Jan 05 2025SCIENCE

Boosting Rice Genome Editing with New Cas9 Variants

Scientists have discovered a new way to make genome editing more efficient in rice. A protein called ScCas9, which comes from bacteria, can recognize a wider range of targets in the DNA than the commonly used protein, SpCas9. However, both ScCas9 and its improved version, Sc++, still don't work very

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