When facing advanced biliary tract cancer (BTC), patients often need second-line chemotherapy after the first treatment fails. This review digs into the available evidence to help doctors and patients make informed choices. By comparing different chemo options using a method called network meta-anal
Treating biliary tract cancer (BTC) is a real challenge. While combining chemotherapy with drugs that target PD-1 protein (called PD-1 inhibitors) might work well, doctors need better ways to predict who will benefit the most. A team at Changzhou First People's Hospital decided to look into this. Th
Imagine you're an adult with appendicitis, a condition where your appendix gets inflamed and causes pain. traditionally, surgery (appendicectomy) has been the go-to fix. But recent studies show that antibiotics could be just as effective and safer. However, different studies use varying methods and
Cancer cells have a sneaky way of hiding from our immune system. One of their tricks involves a molecule called human leukocyte antigen G, or HLA-G for short. Normally, HLA-G helps keep the immune system from attacking our own bodies. But in cancer, this molecule goes rogue. It creates a sort of inv
Phytocompounds, found naturally in plants, are stirring up interest as potential weapons against the parasitic disease leishmaniasis. These compounds hold promise due to their ability to fight against parasites without causing harm to human cells. Scientists are diving into research to figure out ho
Ever wondered how your weight might affect back pain treatment? A recent study looked into this, focusing on the impact of obesity on a common procedure called lumbar transforaminal epidural steroid injections (TFESIs). These injections are often used to relieve pain in the lower back. The research
Scientists have been exploring how different sensors can help in the diagnosis and treatment of common cancers like breast, lung, colorectal, and prostate. By diving into research articles from 1991 to 2021, they found that biosensors are crucial in all these types of cancer. Electrochemical sensors
Imagine a young kid, just 12 or 13, trying their best as a hockey referee. They're learning, growing, and making mistakes, just like anyone else. Now, picture the scene: parents and coaches screaming at them from the sidelines. This isn't fair, is it? Dave Kadun, an experienced official from Alberta
Web-based programs can really help people with mental health issues. But the thing is, many people don't even start or finish these programs. Researchers wanted to know how well an online program called @myTabu worked for people who had committed child sexual abuse or used child sexual exploitation
Ever wondered how a two-drug HIV treatment fares in real life? Let's dive into the facts about Dolutegravir (DTG) and Lamivudine (3TC). Researchers found that people living with HIV who took this combo had high rates of virus suppression and low rates of failure, discontinuation, and drug resistance
