Scientists are pushing the limits of CAR T-cell therapy, a treatment where a patient’s immune cells get rebuilt to hunt down disease. Right now, it works well against certain blood cancers but struggles with solid tumors and autoimmune conditions. Why? The cells often pick the wrong targets, fail to
A former host of a popular home‑makeover show recently shared that her struggle with Hashimoto’s disease has improved dramatically. She revealed on social media that her thyroid antibody count, once as high as 5 000 in October, has fallen to just 257 after a year of careful changes. She cut her s
Patients with autoimmune conditions such as lupus, rheumatoid arthritis or psoriasis face a noticeably higher chance of developing cancer within the first year after their diagnosis. Italian researchers studied more than 356, 000 people and found a 32 % rise in cancer odds during that early period.
Alopecia areata is a long‑term autoimmune condition that causes hair to fall out without scarring. The problem starts when the immune system attacks growing hair follicles, called anagen follicles. Scientists have discovered that Janus kinase (JAK) inhibitors can stop this harmful signaling, givi
Researchers have long known that autoimmune diseases can raise the risk of heart problems. But what about brain bleeds? Specifically, a type called subarachnoid hemorrhage (SAH). It's rare but can be very serious. A recent study tried to find out if autoimmune diseases might play a role in causing S
Scientists have created four new compounds that could be game-changers in the fight against autoimmune diseases and severe infections. These compounds, named IGYZT01046, IGYZT01058, IGYZT01066, and IGYZT01068, were designed to target a key protein called IRAK-4, which plays a big role in these condi
Sometimes, the body sends mixed signals. An elderly person comes in with muscle pain and fatigue. Blood tests show inflammation. Doctors often think of polymyalgia rheumatica (PMR), a common condition. They start treatment with steroids. The patient feels better. But what if it's not PMR? In this c
In the vast realm of biology, small proteins often play significant roles. Striatin-3 is one such protein that frequently draws the attention of the immune system. This isn't unusual. The immune system sometimes mistakenly targets the body's own proteins, leading to autoimmune diseases. Researchers
Autoimmune diseases like rheumatoid arthritis, multiple sclerosis, and lupus are tough to treat. Current treatments just calm down the immune system's attack on the body, but they don't fix the root cause. This means patients often face a lifetime of expensive medications, injections, or infusions w
Neuralgic amyotrophy, also known as Parsonage-Turner syndrome, is a condition that causes sudden pain and weakness in the shoulder area. It is quite common, affecting about 100 out of every 100, 000 people. However, despite its prevalence, there is still a lot we don't know about how it spreads and
