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Dec 30 2024BUSINESS

Big Lots' Big Shift: What's Next for Local Stores?

Big Lots, a well-known retail chain, is shaking things up after filing for bankruptcy last September. They're selling their stores and distribution centers to save jobs and keep their brand alive. The buyers? Gordon Brothers Retail Partners, who'll pass on Big Lots' assets to companies like Variety

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Dec 30 2024CRIME

Tragedy Strikes: South Korea Mourns After Devastating Plane Crash

A grim scene unfolded at Muan International Airport in South Korea after a plane from Bangkok crashed, killing nearly everyone onboard. The Boeing 737-800, carrying mostly Korean passengers returning from holidays, attempted an emergency landing but hit a wall and burst into flames. Only two flight

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Dec 30 2024SPORTS

Hingham Hockey Wins a Thriller in Holiday Classic Final

Boys from Hingham pulled off an exciting 6-5 win against Archbishop Williams in the Arrow Sports Holiday Classic final. This was their first win in this tournament after losing last year. Hingham's head coach, Tony Messina, was back on the bench after missing the semifinal due to illness. He was thr

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Dec 30 2024HEALTH

Could Frame Running Be the Key to Active Living for Kids with Severe Walking Impairments?

Imagine this: a group of kids, laughing and sweating, zooming around in oversized walkers. No, it's not a scene from a futuristic film, but a snapshot from a groundbreaking study exploring the potential of Frame Running. This sport, adapted for those with significant walking impairments, was tested

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Dec 30 2024HEALTH

Exploring Galantamine Modifications for Alzheimer's Treatment

Galantamine, known for its role in managing brain disorders, has been modified to create potential drugs for Alzheimer's disease. Scientists designed and synthesized a variety of galantamine analogues, one of which, named C2, showed great promise. By adding a benzylpyridine ring to galantamine's hyd

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Dec 30 2024ENTERTAINMENT

Staying Safe While Chasing Bigfoot

Two Bigfoot hunters from Oregon met a sad end last weekend. They were searching for the legendary creature in Washington's Gifford Pinchot National Forest. After a days-long search, police found their bodies in a heavily wooded area. The cause? Harsh weather and being poorly prepared. The legend of

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Dec 30 2024HEALTH

Breaking Down Lung Cancer with Triazine: A New Hope

Have you ever wondered why some cancer cells just refuse to die? One of the culprits is a pathway called PI3K/AKT/mTOR, which helps cancer cells grow and divide. Scientists are working on drugs that can shut down this pathway and stop cancer in its tracks. One promising drug is based on a chemical c

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Dec 30 2024HEALTH

Uncovering Depression's Many Faces: A Closer Look at Its Connections to Other Illnesses

Ever thought depression was just a mental health issue? Think again! A recent study dove deep into understanding depression's connections with other diseases. Researchers checked data from over 390, 000 people, including more than 43, 000 with depression. They found that depression is linked to many

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Dec 30 2024HEALTH

Underrated H2B Enzyme Boosts Cancer Cell Strength: A New Target for Immunotherapy

Ever wondered how cancer cells trick the immune system into turning a blind eye? Well, there's an enzyme called Deltex E3 ubiquitin ligase 2, or DTX2, that does just that in liver cancer. Scientists found out that this enzyme helps cancer cells in the liver attract certain immune cells called neutro

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Dec 30 2024SCIENCE

How Low Temperatures Affect Sewage Treatment Biofilms

In cities, sewage treatment plants use unique reactors with moving bed biofilms to clean wastewater. These reactors rely on microbes to break down the waste. Scientists studied how cold temperatures impact these microbes. They found that when it gets cold, the quality of the treated water decreases.

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