Biliary tract cancers are known for their high recurrence rates, even after successful surgery. This makes the future look quite grim for those diagnosed. One common approach to reduce this recurrence risk is to use adjuvant chemotherapy (ACT) after surgery. ACT aims to target and destroy any tiny cancer cells that may have spread before the operation, which the surg...
Advanced biliary tract cancer (BTC) is a tough nut to crack. Doctors often turn to second-line treatments like 5-fluorouracil (5FU) and liposomal irinotecan when first-line therapies fail. These drugs have shown promise in improving survival rates. But what if we could make them even more effective? That’s where nivolumab comes in. Nivolumab is an immunotherapy drug...
Pancreatic cancer, especially the type called pancreatic ductal adenocarcinoma (PDAC), is very dangerous. A medicine called paclitaxel, or PTX, is often given through a needle (intravenously) to treat this cancer. PTX can trigger a special type of cell death that helps the immune system fight cancer. Scientists recently found a way to give PTX as a pill instead of th...
In the realm of breast cancer, the tumor's surrounding tissue, known as the stroma, plays a significant role. One key factor in this stroma is collagen fibers, which can influence the cancer's progression. A recent study delved into the connection between these collagen fibers and how well breast cancer patients respond to pre-surgery chemotherapy, a treatment known ...
Indonesian women who have survived gynecological cancer often face challenges during chemotherapy, like managing side effects and maintaining quality of life. This study is designed to test a digital health intervention called FoRSHE-X. The goal is to help these women cope better with stress, boost their self-confidence, understand and handle chemotherapy side effect...
Our bodies run on a 24-hour rhythm, known as circadian rhythms. These rhythms control many things, like when we sleep and wake up, as well as how our hormones and metabolism work. The main conductor of these rhythms is the circadian clock, located in a small part of the brain called the suprachiasmatic nucleus (SCN). When these rhythms are disrupted, it can lead to ...
In recent years, doctors have been exploring the use of sentinel lymph node biopsy (SLNB) after neoadjuvant chemotherapy (NAC) for a specific group of breast cancer patients. These patients, known as cN3b, have cancer that has spread to both their armpit and the lymph nodes near their breastbone. The study looked into how often SLNB was used for these patients and wh...
Have you ever wondered if more chemotherapy rounds after surgery help patients with stomach cancer that hasn't spread to lymph nodes? This question has not been thoroughly studied, especially for patients who already had chemotherapy before surgery. A multicenter study is now looking into this. The goal? To figure out how many post-surgery chemotherapy cycles improve...
Did you know that HPV, the same virus that causes warts, can also lead to throat cancer? Scientists are exploring a new way to treat this kind of cancer, using a mix of methods. One treatment is called TORS, which is like a robot-assisted operation to remove the tumor from the throat. Another is giving chemotherapy before the operation, called neoadjuvant chemotherap...
Ever wondered how healthcare providers in Guinea handled certain tropical diseases? A recent study looked into this, focusing on diseases like trachoma and onchocerciasis. From November 7th to 22nd, 2022, researchers surveyed 86 healthcare providers in the Forecariah health district. They used a questionnaire to gather information about these workers' understanding a...