Pulmonary sarcomatoid carcinoma (PSC) is an unusual kind of lung cancer that quickly spreads and invades tissues. Typically, it's found at later stages, making surgery challenging. There's no clear best treatment for advanced PSC. Researchers looked at how well chemotherapy and immunotherapy-based treatments work for these patients. Researchers used data from the SE...
Biliary tract cancers, like cholangiocarcinoma and gallbladder cancer, are growing more common worldwide, and most patients get diagnosed when the disease has already advanced, leading to a grim outlook. Recently, combining immune checkpoint inhibitors, such as durvalumab and pembrolizumab, with the standard chemotherapy (gemcitabine plus cisplatin) has shown promisi...
Breast cancer is a big deal, right up there with the second most common cause of cancer deaths among women worldwide. Did you know it can be split into different types based on how aggressive it is, its genetics, and its stage? Despite lots of research, scientists still don't know exactly what causes it. But they have figured out some major risk factors like being a ...
You might be wondering how breast cancer treatment is evolving. One big change is how doctors handle the lymph nodes under the arms. In the past, removing a bunch of these nodes after chemo was standard. But now, research shows that this might not always be necessary. Imagine this: a patient gets chemotherapy first, then has surgery to remove the tumor. In the old d...
Imagine you're a healthcare provider in China, trying to figure out the best treatment for advanced stomach cancer. A recent study, RATIONALE-305, found that combining a drug called tislelizumab with chemo works better than chemo alone. Now, researchers wanted to know if this combo is worth the extra cost. They looked at it from China's healthcare system perspective....
Febrile neutropenia, a severe complication for patients with blood cancers undergoing chemotherapy, is a major concern. This study explored whether Channa striata, a freshwater fish, could help. The goal was to see if extracts from this fish could boost the body's neutrophil count and function, and perhaps even prevent febrile neutropenia in patients with acute myelo...
Chemotherapy is a common treatment for lung adenocarcinoma, but it has its limitations. So, scientists are looking into how it affects our body's defense system. They studied cells from nine patients who either had surgery or chemotherapy before surgery. They found that chemotherapy changes how immune cells like macrophages and T cells behave. In simple words, there...
You might wonder why some breast cancer patients still undergo surgery after chemotherapy. The answer involves a specific group of patients with a particular cancer stage. These patients, whose cancer is classified as ypN1 after neoadjuvant chemotherapy (NAC), are in a bit of a gray area. Doctors aren't sure if they should spare these patients from an additional surg...
Immunotherapy, teamed up with chemotherapy, is giving a big boost to people with advanced, metastatic triple-negative breast cancer (TNBC). This combo helps keep the cancer from spreading for longer than chemotherapy alone. But who's getting the most benefits? That's a question scientists are still trying to figure out. Different groups of TNBC patients might be seei...
Chemotherapy is a game-changer in the fight against cancer. But it can also have some nasty side effects on the heart, like making it weak or causing it to beat irregularly. Doctors often tweak the dose or switch to different treatments to avoid these issues. But what if a natural plant could lend a helping hand? Enter ginseng, a powerful herb packed with compounds c...