Meet rimegepant, a new drug that blocks certain signals in your brain to stop migraines. It's been tested in labs and found to work, but what about in the real world? That's what the GAINER study set out to find. This study, happening in multiple places, looked at how well rimegepant works and how t
Immune-checkpoint inhibitors (ICIs) have emerged as a powerful tool in the fight against advanced squamous cell lung cancer (LUSC). These drugs offer a glimmer of hope for patients who haven't found success with other treatments. But it's not a one-size-fits-all solution—some patients don't respond
Psoriatic arthritis, or PsA, is a complex inflammatory disease that can affect joints and skin, and it often comes with other health issues. Managing PsA is crucial to control the disease, prevent damage, and improve quality of life. Over time, many drugs have been developed to help. While some, lik
Medicines used to treat and prevent heart thrombosis have truly changed the game. They've made a big difference in how patients with heart artery disease do, but they've also made it trickier for doctors to decide on the best treatment. With improved ways to fix heart arteries and better stents, the
Did you know that people with disabilities are more likely to get cancer? Yet, they often can't join cancer clinical trials. Why? Because of rules that measure how well a person can perform daily activities, called performance status. This is set to make sure trial participants aren't too sick. But
In the world of clinical trials, making participants happy is just as important as finding the right cure. But what makes patients satisfied? You might think it's all about the medicine, but there's more to it. Imagine you're at the dentist. You'd be happier if the staff were friendly, right? The s
Ever thought about how new medicines get tested? It's through clinical trials, but they can be a bit of a mess right now. Imagine trying to find a specific book in a huge, disorganized library – that's what it's like for doctors and researchers today. Advocates have a clever idea: create a nati
Over the past few decades, obesity rates have been climbing, with predictions suggesting that nearly half of American adults could be obese by 2030. While changes in lifestyle like diet and exercise often result in a modest 3-5% weight loss, more significant changes are needed to tackle health issue
Isocitrate dehydrogenase (IDH)-mutant gliomas frequently strike young adults, causing severe brain tumors that disrupt their lives. These tumors are notorious for hindering cognitive abilities and, sadly, often lead to death. Current treatments, though life-prolonging, have serious side effects, dam
For years, psychedelic research was put on the backburner due to social and legal reasons. But recently, there's been a surge of interest in these compounds — both natural and synthetic — for treating mental health issues. These psychedelics work by activating specific serotonin receptors in the bra
