CLINICAL TRIALS

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Dec 20 2024HEALTH

Vagus Nerve Stimulation: A New Hope for Severe Depression

Imagine a life changed by a small device. Nick Fournie, now 62, knows this well. His depression journey started 40 years ago, turning his life upside down. Medications caused more harm than good. Then, a nurse suggested vagus nerve stimulation (VNS). This treatment uses electric pulses to stimulate

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Dec 19 2024HEALTH

Inflammation in Atherosclerosis: Beyond Lipid Control

For years, atherosclerosis has been linked to both inflammation and lipid buildup. But even with the best lipid-lowering treatments, some patients still show high inflammatory markers. This is where anti-inflammatory therapies come in, aiming to tackle this leftover risk. Let's explore the main infl

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Dec 15 2024HEALTH

Unlocking the Power of Protein Interactions: New Drugs for Cancer

Proteins are like tiny workers in our bodies, and they often team up to get things done. These partnerships, called protein-protein interactions (PPIs), are crucial for many important jobs, like telling cells when to grow or fixing damaged DNA. When these interactions go wrong, they can cause diseas

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Dec 02 2024HEALTH

Why Information Matters: How Educating Pregnant Women & Health Workers in Kenya Boosts Malaria Fight

Malaria during pregnancy can be dangerous. But with growing resistance to common treatments, new solutions are needed. One promising drug is dihydroartemisinin-piperaquine (DP), which requires taking for several days. Yet, even simple, single-dose treatments often miss the mark. This issue leaves ex

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Nov 30 2024HEALTH

Switching to Tenecteplase: Is It the Smart Move for Stroke Treatment?

Recent trials have shown that tenecteplase, a simpler drug to use, might actually be better than alteplase for treating strokes. Doctors have seen better results with tenecteplase in the long run. Plus, it's easier to administer because you don't need special pumps or constant monitoring. This makes

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Nov 28 2024HEALTH

How Different Image Processing Methods Affect Glioblastoma Treatment Predictions

In a recent study, researchers looked into how various methods of adjusting MRI image brightness and contrast, along with different data batch sizes, influenced the accuracy and reliability of survival predictions for glioblastoma patients from multiple hospitals. They discovered that the way images

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Nov 23 2024HEALTH

Good News or Bad: Primary Outcomes in GI Journal Trials

Scientists and doctors have been buzzing about something interesting. They've found that some clinical trials, especially ones focusing on tummy and liver diseases, might not always stick to their planned main goals. These trials, called randomized controlled trials (RCTs), are designed to test new

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Nov 07 2024CRIME

Fifty Monkeys on the Run in South Carolina

Imagine this: a research facility dedicated to studying monkeys, and suddenly, a group of about 50 monkeys from Alpha Genesis in Yemassee, South Carolina, makes a great escape! This isn't a scene from a movie; it really happened last Wednesday night. The facility, called Alpha Genesis, works with mo

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Oct 06 2024HEALTH

Rwanda Readies for Marburg Trials: Vaccines and Therapeutics on the Way

This weekend, Rwanda will receive experimental vaccines and therapeutics to fight the deadly Marburg virus. These will be used in clinical trials expected to start soon. The virus, similar to Ebola, has caused 41 cases so far, with 12 deaths, mostly among healthcare workers. The government aims to q

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Sep 20 2024HEALTH

The Cancer Conquest: New York's Remarkable Progress

In the past three decades, the chances of dying from cancer have plummeted in New York, and the state's story is a testament to the power of medical advances and public health efforts. The 43.5% drop in cancer death rates between 1991 and 2021 is a staggering achievement, and one that has left exper

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