DRUG DISCOVERY

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Feb 16 2025HEALTH

China's Pharma Shift: From Copycats to Innovators

China's drug scene has seen a huge change in the past 30 years. It used to be all about copying existing medicines, but now it's moving towards creating new ones. This shift is a big deal, but it's not all smooth sailing. One major hurdle is the lack of enough money for local research. Another issue

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Feb 07 2025SCIENCE

Curcumin's Fight Against Cancer: A Molecular Tale

Did you know that there's a compound called curcumin that could help in the fight against cancer? Curcumin is found in turmeric, a spice commonly used in cooking. Scientists are studying how it can be used to target a specific enzyme called Casein Kinase 2 (CK2), which plays a big role in how cells

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Feb 03 2025BUSINESS

From Drugs to Solar Power: The Quantum Leap of Xtalpi

Xtalpi, a Hong Kong-listed company, is making waves in the tech world. It started with a bang in 2016. Wen Shuhao, the company's cofounder and chairman, and his team participated in a blind test. The challenge was to predict the 3D structure of molecules. These molecules show how effective a drug ca

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Jan 29 2025SCIENCE

How Drugs Change Cancer Cell Metabolism

Drugs don't always stop cancer cells from growing, but they often mess with their metabolism. Scientists used a high-tech method, called metabolomics, to see how 1, 520 drugs affected 2, 269 potential metabolites in A549 lung cancer cells. Even though only 26% of the drugs slowed down cell growth, a

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Jan 25 2025HEALTH

Can Old Drugs Fight COVID-19?

Imagine a virus that's causing chaos all around the world. Sounds scary, right? Well, scientists are on a mission to stop this virus, called SARS-CoV-2, from doing more harm. They've discovered that a key part of the virus, called RNA-dependent RNA Polymerase (RdRp), is vital for its growth. So, may

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Jan 22 2025HEALTH

Discovering New Ways to Fight Biliary Tract Cancer

Ever wondered why finding new medicines for biliary tract cancer is so hard? It's not just one disease, but a group of different tumors affecting the inside and outside of the liver's bile ducts, and even the gallbladder. Each type has its own genetic make-up, making it a real puzzle for scientists.

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Jan 22 2025SCIENCE

Fast and Eco-Friendly: Triazoles Made Easy with Ionic Liquids

Triazoles are vital in creating medicines and pesticides. A clever team found a new way to make these molecules using something called ionic liquids. They started with ingredients like benzonitrile derivatives and primary amines, heating them up to create triazoles quickly. What's neat is they could

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Jan 16 2025SCIENCE

Exploring a New Tool for Drug Discovery: The Power of Immobilized Human Serum Albumin

Imagine you're trying to find out how well a new medicine sticks to something in your body, like a sponge. Scientists often use human serum albumin (HSA) for this. Think of HSA as the sponge that helps carry drugs around your body. Recently, scientists created a new tool using HSA stuck to tiny magn

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Jan 09 2025CELEBRITIES

Uncovering Secrets: Allison Holker's Betrayal or Honesty?

In 2022, the world lost Stephen "tWitch" Boss, a dancing gem known for his energetic moves on "The Ellen DeGeneres Show. " Recently, his wife Allison Holker revealed some shocking discoveries she made after his death. In a candid interview, Holker admitted to finding drugs hidden in their closet. Th

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Jan 07 2025HEALTH

Discovering a New Weapon Against Breast Cancer: C-5635020

Breast cancer is a tough enemy, and scientists are always looking for new ways to fight it. One important target is a protein called TGFβ RII. This protein helps cancer cells grow and spread. But finding a drug that can block this protein without causing nasty side effects is like finding a needle i

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