HERA

Dec 31 2024SCIENCE

Discovering Methotrexate's Role in Lung Cancer Treatment

MicroRNAs, or miRNAs, are tiny molecules that can greatly influence how cancer cells grow. Out of all these miRNAs, miR-20b is particularly interesting because it's often out of balance in lung cancer. Scientists used a special computer program to search for small molecules that could tame miR-20b.

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Dec 31 2024SCIENCE

The Hidden Power of Oridonin: A New Player in Cancer Drug Design

Scientists have found a clever way to turn a natural compound into a tool for fighting cancer. This compound, called Oridonin, can help in the design of new drugs called PROTACs. PROTACs are like tiny agents that can hunt and destroy specific proteins in cancer cells. So, what makes Oridonin specia

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Dec 30 2024HEALTH

Are More Statins Necessary After Moderate Dose Success?

Many health guidelines advise specific low-density lipoprotein cholesterol (LDL-C) targets and strong lipid-lowering therapy (LLT) for patients at high risk. But what happens when these targets are met using moderate-intensity statins? Do physicians need to increase LLT further? We explored this que

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Dec 30 2024HEALTH

Boosting Knee Recovery: Early Rehab and Brain Stimulation

You've probably heard that early rehabilitation is key after a sports knee injury. But what if we added something extra to the mix? Let's talk about combining early rehab with a special brain treatment called repetitive transcranial magnetic stimulation (rTMS). Researchers wanted to see if this com

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Dec 30 2024HEALTH

Fish Extracts in Cancer Treatment: A Closer Look

Febrile neutropenia, a severe complication for patients with blood cancers undergoing chemotherapy, is a major concern. This study explored whether Channa striata, a freshwater fish, could help. The goal was to see if extracts from this fish could boost the body's neutrophil count and function, and

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Dec 30 2024BUSINESS

Outlook Therapeutics: Navigating Risks in Supply Chain Dependence

Outlook Therapeutics, known by its ticker OTLK, has recently highlighted a new set of challenges. The company relies heavily on external manufacturers, primarily FUJIFILM Diosynth Biotechnologies, for making and supplying their drug candidates like ONS-5010/LYTENAVA. This outsourcing isn't without i

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Dec 30 2024HEALTH

Blood Therapies for Elderly Trauma Patients: A Comparative Look

Imagine you're an elderly patient hurt in a fall or a car accident and taken to the ER. Your doctor has three options for treating your injuries: whole blood, components of blood, or a combination of both. This study did a deep dive into how these different blood therapies affect elderly patients wi

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Dec 30 2024HEALTH

Underrated H2B Enzyme Boosts Cancer Cell Strength: A New Target for Immunotherapy

Ever wondered how cancer cells trick the immune system into turning a blind eye? Well, there's an enzyme called Deltex E3 ubiquitin ligase 2, or DTX2, that does just that in liver cancer. Scientists found out that this enzyme helps cancer cells in the liver attract certain immune cells called neutro

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Dec 29 2024HEALTH

Soccer Players with Chronic Ankle Instability: VR Games vs. Balance Training

Ever wondered how virtual reality (VR) and balance training compare when it comes to helping soccer players with chronic ankle instability? A recent study checked this out. The researchers rounded up 32 male soccer players with this issue and split them into two groups: one played VR games, and the

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Dec 29 2024HEALTH

Polysaccharides in Cancer Care: A Fresh Look

Cancer treatment has seen some amazing changes lately, with scientists focusing on targeted drug delivery. One interesting way to do this is by using something called anionic polysaccharides. These are like superheroes in the world of medicine because they have cool properties like being non-toxic,

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