Hereditary angioedema (HAE) is a rare condition that causes painful swelling. Two treatments, garadacimab and lanadelumab, were put to the test to see which one works better. Since there are no direct comparisons, researchers used a clever method called matching-adjusted indirect comparison (MAIC) to make an educated guess. Garadacimab was given once a month, while ...

Hereditary angioedema (HAE) is a rare genetic condition. It causes frequent episodes of swelling under the skin or mucous membranes. This swelling is known as angioedema. Current treatments for HAE have their limits. They either block certain proteins in the blood or replace a missing protein. These treatments do not always work well or are not always available. The...