Cancer is a massive health problem around the world. One major breakthrough in fighting cancer is a type of treatment called immune checkpoint inhibitors. These treatments help the body's immune system fight cancer by blocking certain proteins. These proteins are like brakes on the immune system. By releasing these brakes, the immune system can attack cancer cell...
In the world of cancer treatment, immune checkpoint inhibitors (ICIs) have become a big deal. They help the immune system fight cancer. But they might also cause some trouble. One such issue is uveitis, an inflammation of the eye. The question is: do ICIs really increase the risk of uveitis? This is what researchers wanted to find out. They compared ICIs with chemot...
Cancer treatment has seen a big change with immune checkpoint inhibitors (ICIs). These drugs help the body's immune system fight cancer. But, some patients see their cancer grow quickly. This is called hyperprogressive disease (HPD). It's a big problem for doctors and patients. It's important to understand why this happens. ICIs work by blocking certain pro...
Hepatocellular carcinoma (HCC) is a type of liver cancer that is notoriously tough to treat. Doctors have been experimenting with immune checkpoint inhibitors (ICIs) to fight this disease. However, these drugs can sometimes make the cancer grow faster, a condition known as hyperprogressive disease (HPD). This is bad news for patients, as it means the cancer is gettin...
Pleural mesothelioma (PM) is a tough cancer to treat. It's caused by asbestos exposure, and it's not easy to cure. Doctors have been looking for better ways to fight this disease. Recently, they have found some promising results with immune checkpoint inhibitors (ICIs). ICIs are a type of drug that helps the body's immune system recognize and attack cancer cells. ...
Treatment options for epithelial ovarian cancer (EOC) have expanded a lot in recent years, but much of the progress has been tied to picking the right biomarkers. This means there's still a big need for better treatment options to help patients live longer and enjoy better quality of life. Unlike many other types of cancer, using immune checkpoint inhibitors (CPIs) a...
You might not think about it, but the time of day you get your cancer treatment could make a difference. Scientists have been looking into how our body's internal clock, called the circadian rhythm, affects how well cancer drugs work. One type of drug, called immune checkpoint inhibitors (ICIs), has been quite successful in treating advanced biliary tract cancers (BT...
Biliary tract cancers, like cholangiocarcinoma and gallbladder cancer, are growing more common worldwide, and most patients get diagnosed when the disease has already advanced, leading to a grim outlook. Recently, combining immune checkpoint inhibitors, such as durvalumab and pembrolizumab, with the standard chemotherapy (gemcitabine plus cisplatin) has shown promisi...
Immune-checkpoint inhibitors (ICIs) have emerged as a powerful tool in the fight against advanced squamous cell lung cancer (LUSC). These drugs offer a glimmer of hope for patients who haven't found success with other treatments. But it's not a one-size-fits-all solution—some patients don't respond well. Doctors are working hard to identify who might need additional ...
Immuno-oncology drugs, like immune checkpoint inhibitors (ICIs), have shown potential in treating various cancers. For advanced non-small cell lung cancer (NSCLC) patients with PD-L1 expression of 50% or higher, single-drug ICI therapy that targets PD-L1 is the standard treatment. But can machine learning (ML) algorithms do a better job at predicting how well these t...