When you think of diabetes, you probably picture how it affects your blood sugar. But did you know it also messes with how your muscles use fat? That's what we're diving into here. You see, diabetes ties into a whole bunch of health issues, including how your muscles handle fat. When fat builds up in your muscles and causes stress in the powerhouses called mitochond...
Obesity and inactive lifestyles are causing a global surge in type 2 diabetes. One key issue is that fatty foods boost blood fatty acid levels, making it harder for insulin to work properly. This can lead to insulin resistance and type 2 diabetes. Certain proteins, like JNK, IKK-NF-κB, and STAT3, play a role in this resistance. Previously, scientists found that two p...
Obesity can make muscles weak and resistant to insulin. This is known as sarcopenic obesity, and there's no cure yet besides changing your lifestyle and diet. Feruloylacetone (FER) and demethoxyferuloylacetone (DFER) are compounds found in the breakdown of curcumin and bisdemethoxycurcumin. They might help fight obesity's effects on muscles and insulin. In a study, ...
Ever thought about how exercise helps keep your muscles in shape? Well, let's dive into a fascinating study done on rats! When rats eat a high-fat diet, their muscles struggle to store sugar properly. This is a big deal because it can lead to something called insulin resistance, which makes it tough for the body to control blood sugar levels. Now, you might be wonde...
Have you ever felt like making decisions is tough, especially when it comes to putting in effort? People with major depressive disorder (MDD) often face this challenge. Research shows that metabolic issues like insulin resistance and dyslipidemia, which are common in MDD, can mess with our reward system. This study dives into how these metabolic factors can affect ef...
You've probably heard about diabetes and obesity, but have you heard of "diabesity"? It's a mix of both, and it's becoming a big worry for health experts around the world. There's a special marker called the TyG index that can tell if someone might be resistant to insulin, which is linked to lots of health problems. A recent study looked at this index over a long per...
Ever wondered if there's a simple way to tell if you might get diabetes in the future? Scientists have been exploring a new tool called the Metabolic Insulin Resistance Score, or METS-IR for short. This score is like a sneak peek into how well your body handles insulin, which can give us a hint about diabetes risk. But does it really work? And does it matter if you'r...