Ever heard of calmodulin (CaM)? It's a tiny protein that plays a big role in our bodies. One of its jobs is to help control a specific channel called TRPV5, which is crucial for keeping our calcium levels balanced. You see, TRPV5 is like a tiny gate that lets calcium into our kidney cells. But CaM h
Recent studies have sparked a new interest in using a combination of two common drugs, ivermectin and doxycycline, to tackle the COVID-19 virus. By employing advanced computer simulations, researchers have shown that these drugs could potentially hinder the virus' main protease, $3CL^{pro}$. This pr
Esophageal squamous cell carcinoma (ESCC) is a growing concern globally, with limited effective treatments available. There’s a drug called ivermectin that could potentially change the game. Usually used against parasites, ivermectin has shown promise in slowing down cancer growth in lab studies. Sc
The UCLA women's basketball team set the court ablaze with a thrilling 77-62 victory over the mighty South Carolina Gamecocks. This powerful win not only snapped the defending champions' impressive 43-game winning streak but also marked the Bruins' first-ever triumph over a top-ranked team. The Brui
Ever wondered how walking with extra weight changes the way your ankles move? Biomechanists have been diving into this question for a while now. They used some fancy tech like dynamic biplane radiography and model-based 2D-3D tracking to see how the ankle joint complex behaves under extra load. Turn
Imagine you're dealing with high blood pressure that just won't budge, no matter how many pills you take. This is the reality for people with resistant hypertension. They're on all the standard meds like beta-blockers, calcium channel blockers, diuretics, and ACE inhibitors or ARBs, but their blood
Every year, millions suffer from Schistosoma mansoni infections, a nasty parasite that's tough to kick out with regular drugs. Scientists in a lab decided to test a new approach using ivermectin, a drug that usually works against other worms. They wanted to see if boosting ivermectin's potency with
Imagine you're running a massive experiment with tiny worms. You're studying how they evolve resistance to a drug called ivermectin. To do this, you use a cool new tool called TARDIS barcoding. This tool helps you track the worms' genetic lineage, just like a family tree. Why worms? Because the
Soldiers injured in battles often have trouble breathing. One serious problem is called Acute Respiratory Distress Syndrome (ARDS). This happens when the lungs can't get enough oxygen. Doctors and researchers looked into how to best treat this near the battlefield. They found two main methods: mecha
The COVID-19 pandemic taught us a lot about how diseases spread indoors. One big lesson was that crowded, poorly ventilated spaces can be hotspots for infection. Most classrooms in the U. S. don't have mechanical ventilation, so they can fill up with tiny virus particles in the air. Scientists used
