The American Chemical Society has a big job. It has to pick the best of the best in medicinal chemistry. This year, the 2024 ACS Division of Medicinal Chemistry Awards are shining a spotlight on some truly outstanding individuals. These are the people who are making a real difference in how we understand and treat diseases. The awards are a big deal. They recognize ...

Inflammation is a tricky thing. It's like a double-edged sword. It helps the body fight infections and heal injuries, but it can also cause problems when it goes into overdrive. This is where natural products come in. Some plants have special compounds that can calm down inflammation. These compounds are like secret weapons hidden in nature. Scientists have ...

You might have heard of 1, 4-dihydropyridines, or DHPs for short. These tiny molecules pack a big punch when it comes to heart health. They're like little keys that fit perfectly into specific locks on our body's calcium channels. These channels, especially the L-type ones, control how much calcium gets into our muscle cells. DHPs are super selective; they love to ha...

Ever wondered how scientists come up with new medicines? Enter Chemistry42, a smart software platform that uses artificial intelligence (AI) to design new molecules with specific properties. This isn't your average software; it's part of a bigger drug discovery toolkit called Pharma. ai by Insilico Medicine. Chemistry42 isn't just about creating new molecules; it en...

In the world of medicinal chemistry, creating potent drugs involves exploring different structures and their effects. One key challenge is figuring out which drug variations (analogues) to make next. Researchers have come up with a new way to predict and design powerful drugs. This method combines a special computer model that understands chemical language with a too...