A big study looked at how a protein called ApoB, which helps move fats around in your body, might affect a skin condition called atopic dermatitis (AD). This condition causes red, itchy skin and is quite common. The study used data from over 450, 000 people in the UK. Scientists measured ApoB levels in people's blood and then tracked who got AD over time. They found...
Cancer cells are sneaky. They find ways to survive and grow, even when the body tries to stop them. Recent research shows that cancer cells steal fat from the blood. This fat helps them build strong walls and protects them from dying. Cancer cells use special sugar chains to grab fat molecules. These chains act like fishing lines, pulling in fat-packed molecules cal...
Inside the brain, there's a sneaky fight happening. Glioblastoma, a tough type of brain cancer, is always finding ways to survive. Scientists have spotted a clever trick it uses. A tiny helper inside cells, called SH3GLB1, is part of this trick. It helps cells clean up and recycle their own parts. This cleanup, called autophagy, gives glioblastoma an edge. It lets th...
The brain is a busy place, always working to keep you alert or help you sleep. It turns out that special cells called astrocytes play a big role in this switch. These cells are like tiny helpers in the brain. They talk to other brain cells using chemicals called neurotransmitters. One important neurotransmitter is noradrenaline. It helps control how awake or sleepy y...
Genes play a big role in how the body handles medicines. One gene, NFIB, has a specific change (rs28379954 T>C) that can affect how much clozapine, a medicine used for treatment-resistant schizophrenia, is in the blood. People with this change need higher doses to feel the medicine's effects. This study looked at 285 patients taking clozapine. It found that people w...
As people age, a unique health problem often arises. It is called sarcopenic obesity. This condition combines muscle loss with excess fat. It is a growing concern as the population ages. Many factors contribute to this issue. These include long-term inflammation, hormonal shifts, and problems with energy production in cells. However, two key factors stand out. T...
Synthetic cathinones are a big deal in the world of illegal drugs. They are a major type of third-generation drugs that the United Nations keeps an eye on. These substances are known for their rapid development and how quickly they change in the body. The focus here is on a specific type called alpha-pyrrolidinophenone-derived synthetic cathinones. These are often ...
The tropical cockroach, Gromphadorhina coquereliana, has a unique ability to handle cold temperatures. This is quite surprising, as these creatures are ectothermic. This means they rely on their environment to regulate body temperature. This affects many aspects of their lives, from how they grow to how they behave. Their ability to survive in the cold is a big deal....
Polycystic ovary syndrome, or PCOS, is a common issue among women who can have children. It is a problem with hormones and reproduction. Women with PCOS often have trouble with their eggs. This can make it hard for them to have babies. One big question is how fat, specifically fatty acids, affects the eggs in women with PCOS. This is important because fat can change ...
Diabetes can really mess with your heart. It causes issues at the smallest levels in your heart cells. These problems create a complicated mess that makes your heart work poorly. This mess includes messed-up energy use, wonky signals, and too many harmful molecules. It is not just about one thing. It is a mix of several things. This is why people with diabetes ofte...