A compound from a plant is showing promise in the fight against a specific type of cancer. This compound is called ponicidin. It comes from a plant known as Rabdosia rubescens. It has been found to have strong anti-cancer properties. The big question is, how does it work against esophageal squamous cell carcinoma (ESCC)? This is a type of cancer that affects the esop...
Obesity is a major health concern that goes beyond just weight. It is linked to a higher chance of developing cancer. This connection is not just about how much someone weighs. It is about how fat cells behave and interact with other cells in the body. This interaction can lead to cancer in various ways. First, let's talk about hormones. Obesity can cause hormonal i...
Bone tumors, specifically giant cell tumors of bone (GCTB), are tricky. They are not made up of just one type of cell. Instead, they are a mix of different cells. This mix makes them hard to understand and even harder to treat. To make things worse, these tumors are not uniform. They vary from one person to another. This variation is what makes them so challenging. ...
Bile duct cancer, also known as biliary tract cancer, is a serious illness. The outlook for patients has not been great. However, researchers have made big strides in understanding how this cancer grows. This understanding has led to new ways of treating it. The focus now is on finding even better ways to fight this disease. The big question is how to make c...
Ever wondered why some workouts feel more effective than others? It turns out, the time of day you exercise and eat can make a big difference. Your body has an internal clock, called the circadian clock, that controls many of its processes. This clock can influence how your muscles respond to exercise and food. Researchers have found that exercising in the l...
Glioblastoma, a nasty type of brain tumor, has a sneaky way of communicating with its surroundings. It sends out tiny bubbles, called exosomes, that can change how immune cells, called microglia, behave. These exosomes are like secret messengers, carrying instructions that can turn microglia into helpers for the tumor instead of fighters against it. But how do these...
Pregnancy is a big deal for a woman's body. It changes how medicines work in the liver. This is important because many medicines are processed by the liver. The liver's job is to break down and get rid of medicines. During pregnancy, the liver might not work as well. This can change how much medicine gets into the bloodstream and how quickly it leaves the body. So, ...
Ever wondered why doctors keep harping on that liver damage stuff? Well we have a drunk sloshing around inside toxins from cigarettes loving our liver. Why do you think they call the early problems MASLD? NASH didn't go anywhere it switched to MASH Mash is not something we want. The medical world just can't seem to pick the best term of them. Who should be shocked ...
Ever wondered what keeps our blood flowing smoothly? Let the vascular endothelial cells guide the way. These are natural bodyguards. They are flat cells. They line the insides of our blood vessels, providing a first line defense and crucial functions like maintaining blood pressure, keeping blood from thickening, and ensuring smooth blood flow. They are found throu...
Lately, we've been seeing more and more of those pesky cyanobacterial blooms. One of their byproducts, Microcystin-LR (MC-LR), can do a real number on both our environment and our health. Scientists have hinted that it might be causing kidney cells to self-destruct, or go through apoptosis, which is like cells committing suicide. But how exactly does MC-LR trigger th...