The battle against advanced non-small cell lung cancer (aNSCLC) has seen significant strides with targeted therapies and immunotherapies. These treatments have shown promise in extending the lives of patients. However, there is a catch. The cost of these medications is sky-high. This raises important questions about access and affordability. Patients with aN...
In the world of cancer treatments, there is a lot of talk about how to make new drugs work better. One big idea is called performance-based risk-sharing agreements. This is a fancy way of saying that the people who make the drugs and the people who pay for them agree to share the risks and rewards. It is all about making sure that new treatments, like immunotherapy f...
Lung cancer is a serious issue worldwide, and a small fraction of cases are driven by something called RET rearrangements. These are like genetic mix-ups that can fuel cancer growth. To fight this, doctors use special drugs known as RET inhibitors. These drugs have been a game-changer for patients, but there's a catch. Over time, the cancer can become resistant to th...
In the treatment of lung cancer, doctors often use a combination of chemotherapy and radiation. But there is a problem. Sometimes, this mix causes a serious side effect called pneumonitis. This is when the lungs become inflamed. Pneumonitis can be bad enough to stop treatment. But what happens if doctors try to start the treatment again? This is what researcher...
In Brazil, the diagnosis of non-small cell lung cancer often comes too late. This delay pushes up the price of treatment. The financial burden of treating this disease in private healthcare settings is a growing concern. The cost of treating lung cancer can be astronomical. This is especially true when the disease is caught at an advanced stage. In these cases, the ...
Lung cancer is a serious disease that affects many people. In Norway, researchers looked into how different types of advanced non-squamous non-small cell lung cancer (NSCLC) are treated. They focused on patients with specific genetic changes: EGFR+, ALK+, and ROS1+. These genetic changes can make a big difference in how the cancer responds to treatment. The study tr...
Lung cancer is a serious disease that affects many people worldwide. It is important to know that there are different types of lung cancer. One type is called non-small cell lung cancer. This type of cancer can be very tough to treat, especially when it's in its final stage, known as stage IV. Doctors and researchers are always looking for better ways to tr...
Lung cancer is a tricky disease, and one type, non-small cell lung cancer (NSCLC), can be even trickier. Why? Because it can have different mutations, and these mutations can affect how well treatments work. Two of these mutations are called KRAS G12C and KRAS G12D. They are not the same and can behave differently. Doctors and researchers have been studying these mu...
First, let's understand what we're talking about. Lung cancer is a deadly disease. Two ways to fight it are chemoimmunotherapy and immunotherapy. Chemoimmunotherapy is like a two-pronged attack. Chemotherapy uses drugs to kill cancer cells. The chemotherapy part of chemoimmunotherapy has been a standard treatment for a long time. It has proven its worth in the field...
Immuno-oncology drugs, like immune checkpoint inhibitors (ICIs), have shown potential in treating various cancers. For advanced non-small cell lung cancer (NSCLC) patients with PD-L1 expression of 50% or higher, single-drug ICI therapy that targets PD-L1 is the standard treatment. But can machine learning (ML) algorithms do a better job at predicting how well these t...