GT103 is a unique human antibody designed to fight cancer by targeting the complement factor H. Scientists conducted a study to test its safety and effectiveness in patients with tough-to-treat lung cancer. The trial involved gradually increasing the drug's dose to find the highest amount that patients could safely handle. Thirty-one patients participated across thre...

Imagine you're battling advanced malignant melanoma or non-small cell lung cancer. Doctors might use immune checkpoint inhibitors, like those targeting PD-1, to help your body fight the disease. But here’s the thing: only about 20-40% of patients actually see real benefits. So, scientists set out to find some clues in the blood to predict who would benefit. They want...

Have you ever wondered why some cancer cells just refuse to die? One of the culprits is a pathway called PI3K/AKT/mTOR, which helps cancer cells grow and divide. Scientists are working on drugs that can shut down this pathway and stop cancer in its tracks. One promising drug is based on a chemical called triazine. This drug, named 5nh, is really good at blocking two ...