RESISTANCE MECHANISMS

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Dec 21 2025SCIENCE

Unlocking the Secrets of Breast Cancer Treatment Resistance

Breast cancer treatments have come a long way, but resistance to drugs is still a big hurdle. One such drug, trastuzumab deruxtecan (T-DXd), is used to treat breast cancer that has spread and has a specific marker called HER2. However, over time, the cancer often becomes resistant to this treatment.

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Apr 28 2025SCIENCE

The Hidden Power of Rye in Wheat Rust Defense

Wheat is a staple food for many people around the world. It is a major source of carbohydrates and nutrients. It is also a major crop in many countries. But wheat faces a big problem. A disease called stripe rust can wipe out entire fields of wheat. This disease is caused by a fungus. It can s

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Apr 09 2025SCIENCE

The Double-Edged Sword of Herbicide Resistance in Rice

Herbicides are a double-edged sword. They help farmers keep weeds at bay, but they also pose a risk. Weeds can develop resistance, making the herbicides less effective. This is a big problem, especially with paraquat. Paraquat is a fast-acting herbicide used around the world. It's non-selective,

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Mar 19 2025SCIENCE

How Heat Affects Bacteria's Defense Against Antibiotics

Bacteria have clever ways to dodge antibiotics. One of their tricks is using efflux pumps. These pumps act like tiny doors that kick out antibiotics before they can cause harm. This makes bacteria hard to treat. But here is a twist. Temperature changes can mess with these pumps. This is important be

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Dec 15 2024HEALTH

Resistance in Worms: Why Some Drugs Don't Work

Meet Haemonchus contortus, a tiny worm that packs a big punch. It's one of the most troublesome parasites for sheep and goats, mostly because it's become resistant to many drugs. One group of drugs, called macrocyclic lactones (MLs), includes popular ones like ivermectin and moxidectin. Scientists s

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