Mario Cazzola has taken on a new role as an honorary editor for the journal Pulmonary Pharmacology & Therapeutics. This is a big deal because it means he gets to help shape the future of research in this field. But what does this really mean for the world of respiratory medicine? First, let's talk about who Mario Cazzola is. He's a well-known figure in the world of ...
Obesity is a big problem worldwide. It's not just about looking a certain way. It can lead to serious health issues, like type 2 diabetes. Many people try to change their lifestyle to manage their weight. But sometimes, that's not enough. That's where new medicines come in. Scientists have created something new. It's a special kind of peptide. Peptides are like tiny...
Kidney problems are a big deal globally, affecting many people's health. These issues can lead to serious complications, like heart problems and even death. For a long time, the main treatments were drugs that targeted the renin-angiotensin system. These included ACE inhibitors and ARBs. They helped slow down kidney damage and reduce related health risks. In recent ...
A revolution is happening in the world of healing. It involves tiny needles that can do big things. These are not your usual needles. They are called microneedles. Microneedles have been around since 1998. They are great at getting past the body's natural barriers without causing much harm. This makes them perfect for delivering medicines through the skin. Now, scie...
Triple-negative breast cancer is a type of breast cancer that is particularly aggressive. It is known for its fast growth and resistance to many treatments. This cancer relies heavily on a process called glycolysis to fuel its rapid growth. Glycolysis is a way cells turn sugar into energy. In triple-negative breast cancer cells, an enzyme called hexokinase 2 (HK2) pl...
Insulin resistance is a tricky health issue. It happens when the body stops responding well to insulin. This can lead to high blood sugar levels and even diabetes. While changing habits can help, current medicines have their limits. This is where natural solutions come in. Researchers have found two new compounds that might help. They are called 8-hydroxy-dihydroque...
A recent event has brought attention to the risks of gene therapy for Duchenne muscular dystrophy. A 16-year-old boy lost his life after receiving Elevidys, a treatment designed to combat this severe condition. This unfortunate incident marks the first known death associated with this particular therapy. The teenager's passing was due to liver failure, a complication...
Recurring brain tumors are a big problem. Doctors have been trying to find better ways to treat them. One type of brain tumor, called grade 4 glioma, is particularly tough to handle. These tumors often come back, and when they do, it is really hard to treat them. That is why researchers are always looking for new and better treatments. The focus is on a substanc...
Colorectal cancer is a tricky enemy, with mutations in proteins like APC and AXIN boosting the Wnt/β-catenin pathway. The Wnt/β-catenin pathway is a key player in tumor growth and spreading. The pathway can be turned on in an unwanted way, leading to a buildup of β-catenin. This buildup is caused by problems with a process called ubiquitination, which usually keeps β...
You know those tiny viruses that attack bacteria? They're called phages, and scientists are looking at them as a possible way to fight antibiotic-resistant infections. The problem is, phages can target different types of bacteria, making it tricky to find the right one. Existing computer tools don't always get it right. So, a group of scientists created GE-PHI, a sm...