Cholangiocarcinoma (CCA) is a tough cancer to treat. Doctors have a hard time figuring out which treatments will work best for each patient. One big challenge is predicting how well a patient will respond to immunotherapy, a treatment that helps the body's own immune system fight cancer. Researchers are looking into using machine learning to tackle this problem. Mac...
The liver is a vital organ. It has many jobs, including filtering blood and producing bile. Bile is important for digesting fats. The bile ducts are tiny tubes that carry bile from the liver to the small intestine. Sometimes, cancer can grow in these ducts. This is called cholangiocarcinoma. It can happen inside or outside the liver. Doctors have been curious about w...
Neoadjuvant therapy could be a game-changer in treating liver cancer. It is a type of cancer that starts in the bile ducts inside the liver. These bile ducts are like tiny tubes that help move waste from the liver to the gut. It is often caught late and is hard to treat. Doctors are now looking at using newer treatments like immunotherapy and targeted therapy. These...
Ever wondered why finding new medicines for biliary tract cancer is so hard? It's not just one disease, but a group of different tumors affecting the inside and outside of the liver's bile ducts, and even the gallbladder. Each type has its own genetic make-up, making it a real puzzle for scientists. Despite knowing more about the genes gone wrong, patients still face...
Imagine you're having surgery to remove a tumor from your pancreas. Doctors want to know how many nearby lymph nodes to take out. Why? Because it can affect your chances of recovery. In a recent study, doctors looked into the best way to remove lymph nodes during this type of surgery for a specific kind of pancreatic cancer called distal cholangiocarcinoma. They aim...
Thailand has a problem: not enough places to treat sewage properly. This matters because it lets a tiny parasite called Opisthorchis viverrini (OV) lurk in the water and cause a serious liver cancer called cholangiocarcinoma (CCA). The government tried to fix this by making local governments build waste treatment ponds. But most areas still don't have these ponds. So...
Biliary tract cancer, or BTC, starts in the bile ducts inside the liver (intrahepatic cholangiocarcinoma), the main ducts near the liver (extrahepatic cholangiocarcinoma), or the gallbladder (gallbladder cancer). Because symptoms are often vague and there are no routine screenings, most patients don't find out they have it until it's advanced and their outlook isn't ...
In the heart of southern Lao PDR, a silent killer lurks in the form of cholangiocarcinoma (CCA), a deadly liver cancer. This disease is, in part, caused by a tiny parasite called Opisthorchis viverrini (OV). People in high-risk rural communities often eat raw or undercooked river fish, which can carry OV. But it's not just the parasite that's to blame – other factors...
A recent small-scale clinical trial showed that Atractylodes lancea (AL) could help slow down tumor growth and reduce death rates in people with advanced liver cancer. This study looked into figuring out the best dose of AL to use in future trials. The original trial found that doses between 1, 000 and 2, 000 mg were effective. The goal here was to build on that, mak...