Chronic myeloid leukemia, or CML, is a blood cancer that's defined by a specific genetic change. Doctors have been using drugs that target this change, called tyrosine kinase inhibitors, to treat CML. These drugs have been a game-changer, but some patients don't respond well and their condition worsens. Now, scientists are looking deeper into the DNA of CML cells. Th...
Chronic myeloid leukemia (CML) patients face a tough question after hitting remission: what's next? Doctors often lack clear guidelines for managing care at this stage. A recent study tackles this issue by creating a model to predict the risk of relapse. The model focuses on early changes in BCR::ABL1 biomarker levels and how well patients stick to their treatment pl...
Asciminib is a drug that has been making waves in the treatment of chronic myeloid leukemia (CML). The ASC4FIRST study is a phase III trial that compared asciminib with other tyrosine kinase inhibitors (TKIs) chosen by doctors. The results were impressive, showing that asciminib was more effective and had better safety and tolerability. This trial included a subgr...
The bond between a doctor and a patient is crucial in managing chronic myeloid leukemia (CML). This type of cancer affects the blood and bone marrow. It is a lifelong battle. The patient must take medicine every day. Doctors and patients need to be on the same page. They need to agree on the treatment plan. This is called concordance. When this happens, patient...
Imagine you're living in Ethiopia and dealing with chronic myeloid leukemia (CML). This isn't just about staying alive; it's about living well. But how do patients in low-income countries like Ethiopia fare compared to those in wealthier nations? That's what researchers set out to find. They focused on something called health-related quality of life (HRQoL), which i...
Former Hollywood producer Harvey Weinstein, famously accused of sexual assault and recently indicted by a grand jury, is dealing with a new battle: bone marrow cancer. NBC News reported that Weinstein is receiving treatment for chronic myeloid leukemia while in Rikers Island prison. This type of cancer affects the bone marrow, causing it to produce too many white blo...