Histone deacetylase 8 (HDAC8) has been a hot topic in disease research, especially cancer. But finding the right drugs to target HDAC8 without harming other parts of the body has been a real challenge. One interesting approach is using compounds with nitrogen-containing rings, like thiazines or indo
The world of genetic counseling is evolving, and Australia and New Zealand are no exception. These countries are home to a diverse group of professionals who help people understand and cope with genetic disorders. But how diverse is this workforce, and do they have the capacity to meet the needs of
Titanium dioxide nanoparticles, often used in industry and medicine, are not great for male fertility. Research has found that these tiny particles can mess with sperm cells and the blood-testis barrier, which is important for protecting sperm. They cause sperm count to drop and make sperm move slow
Workplace cultural violence can be brutal. It can involve anything from rude remarks about someone's ethnicity to disrespectful comments about their religion or language. This kind of behavior devalues human dignity and can be incredibly harmful. A recent study set out to explore this issue, focusin
The COVID-19 pandemic exposed the crucial role of a country's regulatory abilities. Nations had to fast-track new vaccine technologies amidst scientific uncertainty and political pressure, a particularly tough challenge for middle-income countries with less experience in crisis regulation. How did c
Hollywood Brown, the wide receiver who's been out with a shoulder injury since the preseason, is finally back in the game. The Chiefs announced on Friday that they're activating Brown from the injured reserve list. Brown got hurt on his very first play with the team in the preseason, but he's been p
Scientists have been exploring how an enzyme from Mucor hiemalis, known as Endo-M, can stitch together sugar clusters on cyclodextrins. This enzyme is particularly interested in sugars attached to β-cyclodextrin, which are tiny, donut-shaped molecules. The game changes when these cyclodextrins have
It's a new day for Darien's business community. Mayor Joseph Marchese dropped a surprise announcement on Thursday. The city has taken over the chamber of commerce's events and hired its former executive director. This is all part of the new Darien Business Alliance, which the City Council has just a
Get ready for an exciting event at Universal CityWalk Orlando! This weekend, NBC Sports is setting up a live broadcast for "Football Night in America" right in the heart of CityWalk. The broadcast will take place on the CityWalk Plaza Stage, nestled between Vivo Italian Kitchen and the Epic Universe
New York City's drugstore landscape has seen a significant shrinkage over the past decade, with about 40% fewer stores compared to ten years ago. This year alone saw a 10% drop, attributed largely to rising shoplifting and crime rates. Major pharmacy chains like Walgreens, CVS, and Rite Aid have bee
