Our bodies are powered by complex chemical reactions called metabolism, which involves a vast orchestra of proteins, enzymes, and other molecules. Sometimes, defects in how these molecules work lead to inborn errors of metabolism (IEM), affecting how we produce and break down proteins, fats, and car
Scientists have found something called a Universal Receptive System. It's like a control system for cells, both good and bad ones. This system uses special receptors called TezRs, made from DNA or RNA. They're on the cell's surface, helping cells respond to their environment. A recent study focused
Infertility is a common issue globally, with many cases lacking clear explanations. Interestingly, recent research hints at a connection between how our bodies handle fats (lipids) and our ability to conceive. One particular measure, called the non-high-density lipoprotein cholesterol to high-densit
Scientists have been digging into how lung adenocarcinoma, a type of lung cancer, handles amino acids. They discovered that different lung cancer cells behave differently when it comes to amino acid metabolism. By looking at public databases, they found 163 genes that act differently in lung adenoca
In the heart of Tennessee, a small stream named East Fork Creek has been under close watch. Scientists have been keeping tabs on it for a whole year, from May 2022 to May 2023. They were curious about how the stream's 'breathing' changes with the seasons and time of day. They set up month-long camps
Cancer cells are known for their clever tactics to evade the body's immune system. One of these tricks involves manipulating the metabolic processes of cells in and around the tumor. Tumors gobble up glucose, their main energy source, and produce lactate. This creates a tough environment for immune
Ever wondered what causes gout, that painful arthritis flare-up? It's all about uric acid, and a crucial enzyme called xanthine oxidase (XO). Picture XO as a little worker in our bodies, responsible for producing uric acid from purines like hypoxanthine and xanthine in the final steps of a process c
Chronic cerebral hypoperfusion, or CCH, is a big player in making people's brains work less well over time. This happens when blood flow to the brain is reduced. Part of the puzzle involves how our bodies handle a nutrient called choline. When we eat food with choline, our gut bacteria break it dow
Atopic dermatitis (AD) patients often face lipid metabolism issues, leading to the long-term use of lipid-lowering drugs. However, the influence of circulating lipids and these medications on AD risk remains unclear. To shed light on this, researchers utilized genome-wide association studies (GWAS)
Scientists have been puzzled by the relationship between certain enzymes and cancer. They decided to study mice missing these enzymes to find out more. Over a long period, they noticed that female mice without the DASPO enzyme lived shorter lives. These mice also had strange growths in their liver,
